Posterior wall isolationfor atrial fibrillation: Effects on echocardiographic parameters of cardiac function

Xin Zhang, Neil Beri, Pankaj Malhotra, Rakhee Makhija, Eric Nordsieck, Adam Oesterle, Dali Fan, Nayereh Pezeshkian, Uma Srivatsa

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Background: Posterior wall isolation (PWI) in addition to circumferential pulmonary vein isolation (CPVA) requires more ablation of left atrial tissue. We compared the effect of PWI versus non-PWI methods (CPVA + linear lesions) on echocardiographic parameters of left atrial and left ventricular function. Methods: We selected patients who had pre and post ablation echocardiogram at our institution.Parameters assessed were: Left ventricular outflow tract velocity time integral (VTI), left ventricular ejection fraction (LVEF), atrial Doppler velocity across mitral valve (A), E/E', and deceleration time. Results: Of the 72 patients studied, 32.5% had PWA in addition to CPVA. The mean duration between echocardiograms was 650 + 542 days. PWA group had an average postoperative VTI 0.21 + 0.05 vs 0.21 + 0.05 in the non-PWA (p=0.61) group. Average improvement compared to pre ablation parameters: VTI was 0.03 + 0.06 vs 0.008 + 0.05 (p=0.17), postoperative A was 0.49 + 0.19 vs 0.57 + 0.19 (p=0.16), postoperative LVEF was 57.5 + 9.9% vs 57.8 + 10.8 % (p=0.89), with average change in LVEF 1.5 ± 7.8 vs 0.86 ± 9.7 (p=0.78) in PWA and non-PWA groups respectively. There was no significant difference in change in deceleration time or E/E' when comparing the two groups. Conclusion: PWA did not adversely affect echocardiographic parameters of left atrial function or left ventricular systolic or diastolic function when compared to other types of ablation.

Original languageEnglish (US)
JournalJournal of Atrial Fibrillation
Issue number3
StatePublished - Oct 2020


  • Atrial Fibrillation
  • Posterior Wall Ablation Echocardiogram

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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