Posterior Segment Complications and Impact on Long-Term Visual Outcomes in Eyes With a Type 1 Boston Keratoprosthesis

Ala Moshiri, Mustafa Safi, Lawrence S Morse, Vincent Duong Tang, Glenn Yiu, Susanna Soon Chun Park, Ivan Schwab, Jennifer Li, Mark J Mannis

Research output: Contribution to journalArticle

Abstract

PURPOSE: To determine the spectrum of retinal complications (RCs) in a cohort of eyes with a type 1 Boston keratoprosthesis (KPro). METHODS: All patients (36 eyes of 31 patients) who received a type 1 Boston KPro from January 2004 to December 2015 at the University of California, Davis, were included. Electronic medical records were reviewed for relevant clinical data. Demographic information, initial corneal diagnosis, postoperative course, posterior segment complications, preoperative and final visual acuity were tabulated and analyzed. RESULTS: Posterior segment complications after type 1 Boston KPro were identified in 56% of eyes (n = 20). They included retinal detachment (n = 11; 31%), retroprosthetic membrane (n = 10; 28%), endophthalmitis (n = 7; 19%), cystoid macular edema (n = 5; 14%), epiretinal membrane (n = 4; 11%), vitreous hemorrhage (n = 2; 6%), choroidal detachment (n = 2; 6%), retinal vein occlusion (n = 1; 3%), and macular hole (n = 1; 3%). During the average follow-up period of 53.8 months (median, 57.1 months; range, 1.8-108.7 months) after type 1 Boston KPro, final best-corrected visual acuity improved by a mean of 0.12 logarithm of the minimum angle of resolution (LogMAR) units (range, -2.26 to +2.26) overall. The proportion of eyes with final best-corrected visual acuity better than 20/200 was 2 of 20 (10%) in the group with RCs, in contrast to 7 of 16 eyes (44%) noted among eyes without RCs. CONCLUSIONS: Long-term visual outcomes in eyes after type 1 Boston KPro may depend, in part, on maintaining a healthy posterior pole. Retinal detachment, in particular, may represent a threat to ultimate visual functioning. Regular examination of the peripheral fundus is recommended.

Original languageEnglish (US)
Pages (from-to)1111-1116
Number of pages6
JournalCornea
Volume38
Issue number9
DOIs
StatePublished - Sep 1 2019

Fingerprint

Visual Acuity
Retinal Detachment
Epiretinal Membrane
Vitreous Hemorrhage
Retinal Vein Occlusion
Retinal Perforations
Endophthalmitis
Macular Edema
Electronic Health Records
Demography
Membranes

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Posterior Segment Complications and Impact on Long-Term Visual Outcomes in Eyes With a Type 1 Boston Keratoprosthesis. / Moshiri, Ala; Safi, Mustafa; Morse, Lawrence S; Tang, Vincent Duong; Yiu, Glenn; Park, Susanna Soon Chun; Schwab, Ivan; Li, Jennifer; Mannis, Mark J.

In: Cornea, Vol. 38, No. 9, 01.09.2019, p. 1111-1116.

Research output: Contribution to journalArticle

@article{d0b6171c67d84d35a2e8cec4829d53e7,
title = "Posterior Segment Complications and Impact on Long-Term Visual Outcomes in Eyes With a Type 1 Boston Keratoprosthesis",
abstract = "PURPOSE: To determine the spectrum of retinal complications (RCs) in a cohort of eyes with a type 1 Boston keratoprosthesis (KPro). METHODS: All patients (36 eyes of 31 patients) who received a type 1 Boston KPro from January 2004 to December 2015 at the University of California, Davis, were included. Electronic medical records were reviewed for relevant clinical data. Demographic information, initial corneal diagnosis, postoperative course, posterior segment complications, preoperative and final visual acuity were tabulated and analyzed. RESULTS: Posterior segment complications after type 1 Boston KPro were identified in 56{\%} of eyes (n = 20). They included retinal detachment (n = 11; 31{\%}), retroprosthetic membrane (n = 10; 28{\%}), endophthalmitis (n = 7; 19{\%}), cystoid macular edema (n = 5; 14{\%}), epiretinal membrane (n = 4; 11{\%}), vitreous hemorrhage (n = 2; 6{\%}), choroidal detachment (n = 2; 6{\%}), retinal vein occlusion (n = 1; 3{\%}), and macular hole (n = 1; 3{\%}). During the average follow-up period of 53.8 months (median, 57.1 months; range, 1.8-108.7 months) after type 1 Boston KPro, final best-corrected visual acuity improved by a mean of 0.12 logarithm of the minimum angle of resolution (LogMAR) units (range, -2.26 to +2.26) overall. The proportion of eyes with final best-corrected visual acuity better than 20/200 was 2 of 20 (10{\%}) in the group with RCs, in contrast to 7 of 16 eyes (44{\%}) noted among eyes without RCs. CONCLUSIONS: Long-term visual outcomes in eyes after type 1 Boston KPro may depend, in part, on maintaining a healthy posterior pole. Retinal detachment, in particular, may represent a threat to ultimate visual functioning. Regular examination of the peripheral fundus is recommended.",
author = "Ala Moshiri and Mustafa Safi and Morse, {Lawrence S} and Tang, {Vincent Duong} and Glenn Yiu and Park, {Susanna Soon Chun} and Ivan Schwab and Jennifer Li and Mannis, {Mark J}",
year = "2019",
month = "9",
day = "1",
doi = "10.1097/ICO.0000000000001983",
language = "English (US)",
volume = "38",
pages = "1111--1116",
journal = "Cornea",
issn = "0277-3740",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - Posterior Segment Complications and Impact on Long-Term Visual Outcomes in Eyes With a Type 1 Boston Keratoprosthesis

AU - Moshiri, Ala

AU - Safi, Mustafa

AU - Morse, Lawrence S

AU - Tang, Vincent Duong

AU - Yiu, Glenn

AU - Park, Susanna Soon Chun

AU - Schwab, Ivan

AU - Li, Jennifer

AU - Mannis, Mark J

PY - 2019/9/1

Y1 - 2019/9/1

N2 - PURPOSE: To determine the spectrum of retinal complications (RCs) in a cohort of eyes with a type 1 Boston keratoprosthesis (KPro). METHODS: All patients (36 eyes of 31 patients) who received a type 1 Boston KPro from January 2004 to December 2015 at the University of California, Davis, were included. Electronic medical records were reviewed for relevant clinical data. Demographic information, initial corneal diagnosis, postoperative course, posterior segment complications, preoperative and final visual acuity were tabulated and analyzed. RESULTS: Posterior segment complications after type 1 Boston KPro were identified in 56% of eyes (n = 20). They included retinal detachment (n = 11; 31%), retroprosthetic membrane (n = 10; 28%), endophthalmitis (n = 7; 19%), cystoid macular edema (n = 5; 14%), epiretinal membrane (n = 4; 11%), vitreous hemorrhage (n = 2; 6%), choroidal detachment (n = 2; 6%), retinal vein occlusion (n = 1; 3%), and macular hole (n = 1; 3%). During the average follow-up period of 53.8 months (median, 57.1 months; range, 1.8-108.7 months) after type 1 Boston KPro, final best-corrected visual acuity improved by a mean of 0.12 logarithm of the minimum angle of resolution (LogMAR) units (range, -2.26 to +2.26) overall. The proportion of eyes with final best-corrected visual acuity better than 20/200 was 2 of 20 (10%) in the group with RCs, in contrast to 7 of 16 eyes (44%) noted among eyes without RCs. CONCLUSIONS: Long-term visual outcomes in eyes after type 1 Boston KPro may depend, in part, on maintaining a healthy posterior pole. Retinal detachment, in particular, may represent a threat to ultimate visual functioning. Regular examination of the peripheral fundus is recommended.

AB - PURPOSE: To determine the spectrum of retinal complications (RCs) in a cohort of eyes with a type 1 Boston keratoprosthesis (KPro). METHODS: All patients (36 eyes of 31 patients) who received a type 1 Boston KPro from January 2004 to December 2015 at the University of California, Davis, were included. Electronic medical records were reviewed for relevant clinical data. Demographic information, initial corneal diagnosis, postoperative course, posterior segment complications, preoperative and final visual acuity were tabulated and analyzed. RESULTS: Posterior segment complications after type 1 Boston KPro were identified in 56% of eyes (n = 20). They included retinal detachment (n = 11; 31%), retroprosthetic membrane (n = 10; 28%), endophthalmitis (n = 7; 19%), cystoid macular edema (n = 5; 14%), epiretinal membrane (n = 4; 11%), vitreous hemorrhage (n = 2; 6%), choroidal detachment (n = 2; 6%), retinal vein occlusion (n = 1; 3%), and macular hole (n = 1; 3%). During the average follow-up period of 53.8 months (median, 57.1 months; range, 1.8-108.7 months) after type 1 Boston KPro, final best-corrected visual acuity improved by a mean of 0.12 logarithm of the minimum angle of resolution (LogMAR) units (range, -2.26 to +2.26) overall. The proportion of eyes with final best-corrected visual acuity better than 20/200 was 2 of 20 (10%) in the group with RCs, in contrast to 7 of 16 eyes (44%) noted among eyes without RCs. CONCLUSIONS: Long-term visual outcomes in eyes after type 1 Boston KPro may depend, in part, on maintaining a healthy posterior pole. Retinal detachment, in particular, may represent a threat to ultimate visual functioning. Regular examination of the peripheral fundus is recommended.

UR - http://www.scopus.com/inward/record.url?scp=85071348207&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071348207&partnerID=8YFLogxK

U2 - 10.1097/ICO.0000000000001983

DO - 10.1097/ICO.0000000000001983

M3 - Article

VL - 38

SP - 1111

EP - 1116

JO - Cornea

JF - Cornea

SN - 0277-3740

IS - 9

ER -