Post-transfusion purpura and isoimmune neonatal thrombocytopenia in the same family

E. Cobos, David R Gandara, L. J. Geier, S. Kirmani

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Post-transfusion purpura and isoimmune neonatal thrombocytopenia are rare and unusual syndromes leading to severe thrombocytopenia. In both disorders the PL(A1) platelet antigen is involved in the pathogenesis. A 41-year-old woman with an obstetrical history of isoimmune neonatal thrombocytopenia in two of her children developed post-transfusion purpura following a transfusion of packed red blood cells. Despite the apparent link in these two disorders associated with the PL(A1) platelet antigen, this is the first reported case of post-transfusion purpura and isoimmune neonatal thrombocytopenia occurring in the same family.

Original languageEnglish (US)
Pages (from-to)235-236
Number of pages2
JournalAmerican Journal of Hematology
Volume32
Issue number3
StatePublished - 1989
Externally publishedYes

ASJC Scopus subject areas

  • Hematology

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