Post-transfusion purpura and isoimmune neonatal thrombocytopenia are rare and unusual syndromes leading to severe thrombocytopenia. In both disorders the PL(A1) platelet antigen is involved in the pathogenesis. A 41-year-old woman with an obstetrical history of isoimmune neonatal thrombocytopenia in two of her children developed post-transfusion purpura following a transfusion of packed red blood cells. Despite the apparent link in these two disorders associated with the PL(A1) platelet antigen, this is the first reported case of post-transfusion purpura and isoimmune neonatal thrombocytopenia occurring in the same family.
|Original language||English (US)|
|Number of pages||2|
|Journal||American Journal of Hematology|
|State||Published - 1989|
ASJC Scopus subject areas