Positron emission tomography in male violent offenders with schizophrenia

Michael T H Wong, Peter B C Fenwick, John Lumsden, George W. Fenton, Michael N. Maisey, Petra Lewis, Ramsey D Badawi

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

The FDG PET brain scans from 31 offenders with schizophrenia and schizoaffective disorder from a maximum security mental hospital were compared with those of normal controls (N = 6) in terms of relative FDG uptake in a range of regions covering frontal and temporal regions. The patient sample was divided into those who had a history of repetitive violent offending (RVO, N = 17) and those without a repetitive violent history (NRVO, N = 14) according to the violence rating of their pre-admission convictions. Reduced FDG uptake was noted at both the right and left anterior inferior temporal (R and LAIT) regions in NRVOs but only at LAIT in RVOs. NRVOs had significantly lower FDG uptake at RAIT than RVOs. The findings suggest that metabolic changes at AIT may be related to different patterns of violent offending in patients with schizophrenia.

Original languageEnglish (US)
Pages (from-to)111-123
Number of pages13
JournalPsychiatry Research - Neuroimaging
Volume68
Issue number2-3
DOIs
StatePublished - Feb 7 1997
Externally publishedYes

Fingerprint

Temporal Lobe
Positron-Emission Tomography
Schizophrenia
Psychiatric Hospitals
Violence
Psychotic Disorders
History
Brain

Keywords

  • aggression
  • anterior inferior temporal regions
  • FDG
  • forensic
  • mental hospital
  • repetitive violence

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Radiology Nuclear Medicine and imaging
  • Biological Psychiatry
  • Psychology(all)

Cite this

Wong, M. T. H., Fenwick, P. B. C., Lumsden, J., Fenton, G. W., Maisey, M. N., Lewis, P., & Badawi, R. D. (1997). Positron emission tomography in male violent offenders with schizophrenia. Psychiatry Research - Neuroimaging, 68(2-3), 111-123. https://doi.org/10.1016/S0925-4927(96)02621-2

Positron emission tomography in male violent offenders with schizophrenia. / Wong, Michael T H; Fenwick, Peter B C; Lumsden, John; Fenton, George W.; Maisey, Michael N.; Lewis, Petra; Badawi, Ramsey D.

In: Psychiatry Research - Neuroimaging, Vol. 68, No. 2-3, 07.02.1997, p. 111-123.

Research output: Contribution to journalArticle

Wong, MTH, Fenwick, PBC, Lumsden, J, Fenton, GW, Maisey, MN, Lewis, P & Badawi, RD 1997, 'Positron emission tomography in male violent offenders with schizophrenia', Psychiatry Research - Neuroimaging, vol. 68, no. 2-3, pp. 111-123. https://doi.org/10.1016/S0925-4927(96)02621-2
Wong MTH, Fenwick PBC, Lumsden J, Fenton GW, Maisey MN, Lewis P et al. Positron emission tomography in male violent offenders with schizophrenia. Psychiatry Research - Neuroimaging. 1997 Feb 7;68(2-3):111-123. https://doi.org/10.1016/S0925-4927(96)02621-2
Wong, Michael T H ; Fenwick, Peter B C ; Lumsden, John ; Fenton, George W. ; Maisey, Michael N. ; Lewis, Petra ; Badawi, Ramsey D. / Positron emission tomography in male violent offenders with schizophrenia. In: Psychiatry Research - Neuroimaging. 1997 ; Vol. 68, No. 2-3. pp. 111-123.
@article{f4e052a6431a40fa8b090c8f2cfa5828,
title = "Positron emission tomography in male violent offenders with schizophrenia",
abstract = "The FDG PET brain scans from 31 offenders with schizophrenia and schizoaffective disorder from a maximum security mental hospital were compared with those of normal controls (N = 6) in terms of relative FDG uptake in a range of regions covering frontal and temporal regions. The patient sample was divided into those who had a history of repetitive violent offending (RVO, N = 17) and those without a repetitive violent history (NRVO, N = 14) according to the violence rating of their pre-admission convictions. Reduced FDG uptake was noted at both the right and left anterior inferior temporal (R and LAIT) regions in NRVOs but only at LAIT in RVOs. NRVOs had significantly lower FDG uptake at RAIT than RVOs. The findings suggest that metabolic changes at AIT may be related to different patterns of violent offending in patients with schizophrenia.",
keywords = "aggression, anterior inferior temporal regions, FDG, forensic, mental hospital, repetitive violence",
author = "Wong, {Michael T H} and Fenwick, {Peter B C} and John Lumsden and Fenton, {George W.} and Maisey, {Michael N.} and Petra Lewis and Badawi, {Ramsey D}",
year = "1997",
month = "2",
day = "7",
doi = "10.1016/S0925-4927(96)02621-2",
language = "English (US)",
volume = "68",
pages = "111--123",
journal = "Psychiatry Research - Neuroimaging",
issn = "0925-4927",
publisher = "Elsevier Ireland Ltd",
number = "2-3",

}

TY - JOUR

T1 - Positron emission tomography in male violent offenders with schizophrenia

AU - Wong, Michael T H

AU - Fenwick, Peter B C

AU - Lumsden, John

AU - Fenton, George W.

AU - Maisey, Michael N.

AU - Lewis, Petra

AU - Badawi, Ramsey D

PY - 1997/2/7

Y1 - 1997/2/7

N2 - The FDG PET brain scans from 31 offenders with schizophrenia and schizoaffective disorder from a maximum security mental hospital were compared with those of normal controls (N = 6) in terms of relative FDG uptake in a range of regions covering frontal and temporal regions. The patient sample was divided into those who had a history of repetitive violent offending (RVO, N = 17) and those without a repetitive violent history (NRVO, N = 14) according to the violence rating of their pre-admission convictions. Reduced FDG uptake was noted at both the right and left anterior inferior temporal (R and LAIT) regions in NRVOs but only at LAIT in RVOs. NRVOs had significantly lower FDG uptake at RAIT than RVOs. The findings suggest that metabolic changes at AIT may be related to different patterns of violent offending in patients with schizophrenia.

AB - The FDG PET brain scans from 31 offenders with schizophrenia and schizoaffective disorder from a maximum security mental hospital were compared with those of normal controls (N = 6) in terms of relative FDG uptake in a range of regions covering frontal and temporal regions. The patient sample was divided into those who had a history of repetitive violent offending (RVO, N = 17) and those without a repetitive violent history (NRVO, N = 14) according to the violence rating of their pre-admission convictions. Reduced FDG uptake was noted at both the right and left anterior inferior temporal (R and LAIT) regions in NRVOs but only at LAIT in RVOs. NRVOs had significantly lower FDG uptake at RAIT than RVOs. The findings suggest that metabolic changes at AIT may be related to different patterns of violent offending in patients with schizophrenia.

KW - aggression

KW - anterior inferior temporal regions

KW - FDG

KW - forensic

KW - mental hospital

KW - repetitive violence

UR - http://www.scopus.com/inward/record.url?scp=0031557103&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031557103&partnerID=8YFLogxK

U2 - 10.1016/S0925-4927(96)02621-2

DO - 10.1016/S0925-4927(96)02621-2

M3 - Article

C2 - 9104758

AN - SCOPUS:0031557103

VL - 68

SP - 111

EP - 123

JO - Psychiatry Research - Neuroimaging

JF - Psychiatry Research - Neuroimaging

SN - 0925-4927

IS - 2-3

ER -