Portal site metastasis after thoracoscopic resection of a cranial mediastinal mass in a dog

Sarah G J Alwen, William T Culp, Anna Szivek, Philipp Mayhew, Christina D. Eckstrand

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Case Description—An 11-year-old castrated male Vizsla was evaluated for excision of a cranial mediastinal mass. Clinical Findings—The dog had a 1-month history of a cough that had recently increased in frequency. On physical examination, the dog had a grade 2/6 left systolic heart murmur and multiple subcutaneous masses. A soft tissue mass was observed in the cranioventral aspect of the thorax on radiographs. Results of a CT scan revealed a well-defined, 2.8 X 3.2 X 3.9-cm soft tissue mass in the cranial mediastinum. Treatment and Outcome—The dog underwent video-assisted thoracoscopic removal of the mediastinal mass and recovered routinely. Histologic examination of excised tissues revealed malignant thymoma. Approximately 6.5 months after surgery, the dog was evaluated because of polyuria, polydipsia, decreased appetite, and vomiting. On physical examination, masses were found in both axillary regions. Results of serum biochemical analysis indicated hypercalcemia. Thoracic ultrasonography revealed pulmonary metastases and a large mass in the right caudoventral region of the thorax. The dog received supportive care and medical treatment for hypercalcemia, but clinical signs recurred. Euthanasia was elected; necropsy and histologic examination revealed thymic carcinoma. Conclusions and Clinical Relevance—Descriptions of the development of portal site metastasis in canine patients are rare. In this patient, portal site metastasis developed rapidly after thoracoscopic resection of a malignant thymic mass and was associated with hypercalcemia. As use of thoracoscopic procedures increases in veterinary medicine, it will be important to monitor the development of major complications such as those in the patient of this report.

Original languageEnglish (US)
Pages (from-to)793-800
Number of pages8
JournalJournal of the American Veterinary Medical Association
Volume247
Issue number7
DOIs
StatePublished - Oct 1 2015

Fingerprint

resection
metastasis
Dogs
Neoplasm Metastasis
Hypercalcemia
dogs
hypercalcemia
Thymoma
Thorax
Physical Examination
Systolic Murmurs
Polydipsia
Heart Murmurs
thorax
Polyuria
Veterinary Medicine
Euthanasia
clinical examination
Mediastinum
Appetite

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Portal site metastasis after thoracoscopic resection of a cranial mediastinal mass in a dog. / Alwen, Sarah G J; Culp, William T; Szivek, Anna; Mayhew, Philipp; Eckstrand, Christina D.

In: Journal of the American Veterinary Medical Association, Vol. 247, No. 7, 01.10.2015, p. 793-800.

Research output: Contribution to journalArticle

@article{00ae6ef37ba345a5a6a3b97981e6adb9,
title = "Portal site metastasis after thoracoscopic resection of a cranial mediastinal mass in a dog",
abstract = "Case Description—An 11-year-old castrated male Vizsla was evaluated for excision of a cranial mediastinal mass. Clinical Findings—The dog had a 1-month history of a cough that had recently increased in frequency. On physical examination, the dog had a grade 2/6 left systolic heart murmur and multiple subcutaneous masses. A soft tissue mass was observed in the cranioventral aspect of the thorax on radiographs. Results of a CT scan revealed a well-defined, 2.8 X 3.2 X 3.9-cm soft tissue mass in the cranial mediastinum. Treatment and Outcome—The dog underwent video-assisted thoracoscopic removal of the mediastinal mass and recovered routinely. Histologic examination of excised tissues revealed malignant thymoma. Approximately 6.5 months after surgery, the dog was evaluated because of polyuria, polydipsia, decreased appetite, and vomiting. On physical examination, masses were found in both axillary regions. Results of serum biochemical analysis indicated hypercalcemia. Thoracic ultrasonography revealed pulmonary metastases and a large mass in the right caudoventral region of the thorax. The dog received supportive care and medical treatment for hypercalcemia, but clinical signs recurred. Euthanasia was elected; necropsy and histologic examination revealed thymic carcinoma. Conclusions and Clinical Relevance—Descriptions of the development of portal site metastasis in canine patients are rare. In this patient, portal site metastasis developed rapidly after thoracoscopic resection of a malignant thymic mass and was associated with hypercalcemia. As use of thoracoscopic procedures increases in veterinary medicine, it will be important to monitor the development of major complications such as those in the patient of this report.",
author = "Alwen, {Sarah G J} and Culp, {William T} and Anna Szivek and Philipp Mayhew and Eckstrand, {Christina D.}",
year = "2015",
month = "10",
day = "1",
doi = "10.2460/javma.247.7.793",
language = "English (US)",
volume = "247",
pages = "793--800",
journal = "Journal of the American Veterinary Medical Association",
issn = "0003-1488",
publisher = "American Veterinary Medical Association",
number = "7",

}

TY - JOUR

T1 - Portal site metastasis after thoracoscopic resection of a cranial mediastinal mass in a dog

AU - Alwen, Sarah G J

AU - Culp, William T

AU - Szivek, Anna

AU - Mayhew, Philipp

AU - Eckstrand, Christina D.

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Case Description—An 11-year-old castrated male Vizsla was evaluated for excision of a cranial mediastinal mass. Clinical Findings—The dog had a 1-month history of a cough that had recently increased in frequency. On physical examination, the dog had a grade 2/6 left systolic heart murmur and multiple subcutaneous masses. A soft tissue mass was observed in the cranioventral aspect of the thorax on radiographs. Results of a CT scan revealed a well-defined, 2.8 X 3.2 X 3.9-cm soft tissue mass in the cranial mediastinum. Treatment and Outcome—The dog underwent video-assisted thoracoscopic removal of the mediastinal mass and recovered routinely. Histologic examination of excised tissues revealed malignant thymoma. Approximately 6.5 months after surgery, the dog was evaluated because of polyuria, polydipsia, decreased appetite, and vomiting. On physical examination, masses were found in both axillary regions. Results of serum biochemical analysis indicated hypercalcemia. Thoracic ultrasonography revealed pulmonary metastases and a large mass in the right caudoventral region of the thorax. The dog received supportive care and medical treatment for hypercalcemia, but clinical signs recurred. Euthanasia was elected; necropsy and histologic examination revealed thymic carcinoma. Conclusions and Clinical Relevance—Descriptions of the development of portal site metastasis in canine patients are rare. In this patient, portal site metastasis developed rapidly after thoracoscopic resection of a malignant thymic mass and was associated with hypercalcemia. As use of thoracoscopic procedures increases in veterinary medicine, it will be important to monitor the development of major complications such as those in the patient of this report.

AB - Case Description—An 11-year-old castrated male Vizsla was evaluated for excision of a cranial mediastinal mass. Clinical Findings—The dog had a 1-month history of a cough that had recently increased in frequency. On physical examination, the dog had a grade 2/6 left systolic heart murmur and multiple subcutaneous masses. A soft tissue mass was observed in the cranioventral aspect of the thorax on radiographs. Results of a CT scan revealed a well-defined, 2.8 X 3.2 X 3.9-cm soft tissue mass in the cranial mediastinum. Treatment and Outcome—The dog underwent video-assisted thoracoscopic removal of the mediastinal mass and recovered routinely. Histologic examination of excised tissues revealed malignant thymoma. Approximately 6.5 months after surgery, the dog was evaluated because of polyuria, polydipsia, decreased appetite, and vomiting. On physical examination, masses were found in both axillary regions. Results of serum biochemical analysis indicated hypercalcemia. Thoracic ultrasonography revealed pulmonary metastases and a large mass in the right caudoventral region of the thorax. The dog received supportive care and medical treatment for hypercalcemia, but clinical signs recurred. Euthanasia was elected; necropsy and histologic examination revealed thymic carcinoma. Conclusions and Clinical Relevance—Descriptions of the development of portal site metastasis in canine patients are rare. In this patient, portal site metastasis developed rapidly after thoracoscopic resection of a malignant thymic mass and was associated with hypercalcemia. As use of thoracoscopic procedures increases in veterinary medicine, it will be important to monitor the development of major complications such as those in the patient of this report.

UR - http://www.scopus.com/inward/record.url?scp=84941886273&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941886273&partnerID=8YFLogxK

U2 - 10.2460/javma.247.7.793

DO - 10.2460/javma.247.7.793

M3 - Article

C2 - 26383756

AN - SCOPUS:84941886273

VL - 247

SP - 793

EP - 800

JO - Journal of the American Veterinary Medical Association

JF - Journal of the American Veterinary Medical Association

SN - 0003-1488

IS - 7

ER -