Portable and cost-effective pixel super-resolution on-chip microscope for telemedicine applications.

Waheb Bishara, Uzair Sikora, Onur Mudanyali, Ting Wei Su, Oguzhan Yaglidere, Shirley Luckhart, Aydogan Ozcan

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

We report a field-portable lensless on-chip microscope with a lateral resolution of <1 μm and a large field-of-view of ~24 mm(2). This microscope is based on digital in-line holography and a pixel super-resolution algorithm to process multiple lensfree holograms and obtain a single high-resolution hologram. In its compact and cost-effective design, we utilize 23 light emitting diodes butt-coupled to 23 multi-mode optical fibers, and a simple optical filter, with no moving parts. Weighing only ~95 grams, we demonstrate the performance of this field-portable microscope by imaging various objects including human malaria parasites in thin blood smears.

Original languageEnglish (US)
Pages (from-to)8207-8210
Number of pages4
JournalConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
Volume2011
StatePublished - 2011
Externally publishedYes

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ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

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