Portable and cost-effective pixel super-resolution on-chip microscope for telemedicine applications

Waheb Bishara, Uzair Sikora, Onur Mudanyali, Ting Wei Su, Oguzhan Yaglidere, Shirley Luckhart, Aydogan Ozcan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report a field-portable lensless on-chip microscope with a lateral resolution of 1m and a large field-of-view of 24mm 2. This microscope is based on digital in-line holography and a pixel super-resolution algorithm to process multiple lensfree holograms and obtain a single high-resolution hologram. In its compact and cost-effective design, we utilize 23 light emitting diodes butt-coupled to 23 multi-mode optical fibers, and a simple optical filter, with no moving parts. Weighing only 95 grams, we demonstrate the performance of this field-portable microscope by imaging various objects including human malaria parasites in thin blood smears.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Pages8207-8210
Number of pages4
DOIs
StatePublished - 2011
Event33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States
Duration: Aug 30 2011Sep 3 2011

Other

Other33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
CountryUnited States
CityBoston, MA
Period8/30/119/3/11

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ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Bishara, W., Sikora, U., Mudanyali, O., Su, T. W., Yaglidere, O., Luckhart, S., & Ozcan, A. (2011). Portable and cost-effective pixel super-resolution on-chip microscope for telemedicine applications. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 8207-8210). [6092024] https://doi.org/10.1109/IEMBS.2011.6092024