Polycystic kidney disease in four British shorthair cats with successful treatment of bacterial cyst infection

R. Nivy, Leslie A Lyons, I. Aroch, G. Segev

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Polycystic kidney disease is the most common inherited disorder in cats. Renal cysts progressively increase in size and number, resulting in a gradual decrease in kidney function. An autosomal dominant mutation in exon 29 of the polycystin-1 gene has been identified, mostly in Persian and Persian-related breeds. This case study describes polycystic kidney disease in four British shorthair cats, of which two had the same genetic mutation reported in Persian and Persian-related cats. This likely reflects introduction of this mutation into the British shorthair breeding line because of previous outcrossing with Persian cats. An infected renal cyst was diagnosed and successfully treated in one of the cats. This is a commonly reported complication in human polycystic kidney disease, and to the authors' knowledge has not previously been reported in cats with polycystic kidney disease.

Original languageEnglish (US)
Pages (from-to)585-589
Number of pages5
JournalJournal of Small Animal Practice
Volume56
Issue number9
DOIs
StatePublished - Sep 1 2015
Externally publishedYes

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Polycystic Kidney Diseases
Bacterial Infections
Cysts
Cats
cats
infection
mutation
Kidney
Mutation
Therapeutics
kidneys
genetic disorders
renal function
outcrossing
breeding lines
exons
Breeding
polycystic kidney diseases
Exons
case studies

ASJC Scopus subject areas

  • Small Animals
  • Medicine(all)

Cite this

Polycystic kidney disease in four British shorthair cats with successful treatment of bacterial cyst infection. / Nivy, R.; Lyons, Leslie A; Aroch, I.; Segev, G.

In: Journal of Small Animal Practice, Vol. 56, No. 9, 01.09.2015, p. 585-589.

Research output: Contribution to journalArticle

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