Plexiform neurofibromatosis of the mediastinum: CT appearance

P. M. Bourgouin, J. O. Shepard, Elizabeth H Moore, T. C. McLoud

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


We studied the CT findings in four patients with pathologically proved thoracic plexiform neurofibromatosis. In all four patients, CT showed an infiltrative process and masses that involved the mediastinum along the distribution of the sympathetic chains, phrenic, and vagus nerve. The lesions had lower attenuation values than did chest-wall muscle. In one patient, CT revealed calcifications and peripheral enhancement of nodular components after IV infusion of contrast material. In the appropriate clinical setting, CT detection of lesions in the distribution of the mediastinal nerves strongly favors the diagnosis of plexiform neurofibromatosis.

Original languageEnglish (US)
Pages (from-to)461-463
Number of pages3
JournalAmerican Journal of Roentgenology
Issue number3
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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