Pleomorphic myxoid liposarcoma in an adolescent with Li–Fraumeni syndrome

Tiffany J. Sinclair; Chad M. Thorson; Elysia Alvarez; Serena Tan; Sheri L. Spunt; Stephanie D. Chao

doi:10.1007/s00383-017-4063-x

Pleomorphic myxoid liposarcoma in an adolescent with Li–Fraumeni syndrome

Tiffany J. Sinclair, Chad M. Thorson, Elysia Alvarez, Serena Tan, Sheri L. Spunt, Stephanie D. Chao

Research output: Contribution to journal › Article

7 Scopus citations

Abstract

We present the case of a 15-year-old female with a right perineal mass that was found to be pleomorphic myxoid liposarcoma, a recently recognized, rare subtype of liposarcoma. The patient had a strong family history of malignancy and genetic screening revealed a pathogenic TP53 mutation consistent with Li–Fraumeni syndrome.

Original language	English (US)
Pages (from-to)	631-635
Number of pages	5
Journal	Pediatric Surgery International
Volume	33
Issue number	5
DOIs	https://doi.org/10.1007/s00383-017-4063-x
State	Published - May 1 2017
Externally published	Yes

Fingerprint

Keywords

Hereditary cancer syndrome
Li–Fraumeni syndrome
Sarcoma
TP53 mutation

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Surgery

Cite this

Sinclair, T. J., Thorson, C. M., Alvarez, E., Tan, S., Spunt, S. L., & Chao, S. D. (2017). Pleomorphic myxoid liposarcoma in an adolescent with Li–Fraumeni syndrome. Pediatric Surgery International, 33(5), 631-635. https://doi.org/10.1007/s00383-017-4063-x

@article{340f43cd17384053965487dfd5ddf662,

title = "Pleomorphic myxoid liposarcoma in an adolescent with Li–Fraumeni syndrome",

abstract = "We present the case of a 15-year-old female with a right perineal mass that was found to be pleomorphic myxoid liposarcoma, a recently recognized, rare subtype of liposarcoma. The patient had a strong family history of malignancy and genetic screening revealed a pathogenic TP53 mutation consistent with Li–Fraumeni syndrome.",

keywords = "Hereditary cancer syndrome, Li–Fraumeni syndrome, Sarcoma, TP53 mutation",

author = "Sinclair, {Tiffany J.} and Thorson, {Chad M.} and Elysia Alvarez and Serena Tan and Spunt, {Sheri L.} and Chao, {Stephanie D.}",

year = "2017",

month = may

day = "1",

doi = "10.1007/s00383-017-4063-x",

language = "English (US)",

volume = "33",

pages = "631--635",

journal = "Pediatric Surgery International",

issn = "0179-0358",

publisher = "Springer Verlag",

number = "5",

}

TY - JOUR

T1 - Pleomorphic myxoid liposarcoma in an adolescent with Li–Fraumeni syndrome

AU - Sinclair, Tiffany J.

AU - Thorson, Chad M.

AU - Alvarez, Elysia

AU - Tan, Serena

AU - Spunt, Sheri L.

AU - Chao, Stephanie D.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - We present the case of a 15-year-old female with a right perineal mass that was found to be pleomorphic myxoid liposarcoma, a recently recognized, rare subtype of liposarcoma. The patient had a strong family history of malignancy and genetic screening revealed a pathogenic TP53 mutation consistent with Li–Fraumeni syndrome.

AB - We present the case of a 15-year-old female with a right perineal mass that was found to be pleomorphic myxoid liposarcoma, a recently recognized, rare subtype of liposarcoma. The patient had a strong family history of malignancy and genetic screening revealed a pathogenic TP53 mutation consistent with Li–Fraumeni syndrome.

KW - Hereditary cancer syndrome

KW - Li–Fraumeni syndrome

KW - Sarcoma

KW - TP53 mutation

UR - http://www.scopus.com/inward/record.url?scp=85011635966&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85011635966&partnerID=8YFLogxK

U2 - 10.1007/s00383-017-4063-x

DO - 10.1007/s00383-017-4063-x

M3 - Article

C2 - 28160093

AN - SCOPUS:85011635966

VL - 33

SP - 631

EP - 635

JO - Pediatric Surgery International

JF - Pediatric Surgery International

SN - 0179-0358

IS - 5

ER -

Access to Document

10.1007/s00383-017-4063-x