Plasmodium development in the mosquito: biology bottlenecks and opportunities for mathematical modeling

Anna L. Drexler, Yoram Vodovotz, Shirley Luckhart

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Quantitative analyses of malaria parasite development are necessary to assess the efficacy of control measures. Such analyses in the mammalian host have been difficult to implement, lagging behind the use of antiparasitic drugs, vaccine development and transmission-blocking strategies. Even less is known about the genetic, environmental and other factors that impact sporogony in the mosquito host. Here, we summarize current knowledge and review a first attempt to model sporogonic development quantitatively.

Original languageEnglish (US)
Pages (from-to)333-336
Number of pages4
JournalTrends in Parasitology
Volume24
Issue number8
DOIs
StatePublished - Aug 2008

ASJC Scopus subject areas

  • Infectious Diseases
  • Parasitology

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