Plasma proteins of the pregnant and normal rhesus monkey (Macaca mulatta). A two dimensional electrophoretic study

Plasma proteins from normal and pregnant rhesus monkeys were examined using 2 dimensional gradient acrylamide gel electrophoresis. Histochemical and autoradiographic techniques were used to identify haptoglobin, hemoglobin, lipoprotein, glycoprotein, and transferrin fractions. No 'pregnancy protein' as seen in pregnant human plasma was noted. Previously reported quantitative changes in albumin, α₁, α₂, β, fibrinogen, and γ protein groups were not seen to reflect the appearance of any new pregnancy specific protein(s). Fibrinogen was seen to markedly increase throughout pregnancy.