Abstract
Pituitary adenomas from 15 patients with Cushing's disease were studied histopathologically. The tumors were examined for the presence of neural axons by the Bodian silver impregnation technique and a specific immunohistologic technique based on a monoclonal antibody to axonal neurofilaments. Axons were not seen in any of the surgical specimens. This finding suggests that most, if not all, adrenocorticotropin-secreting pituitary adenomas are of anterior lobe origin.
Original language | English (US) |
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Pages (from-to) | 125-130 |
Number of pages | 6 |
Journal | Surgical Neurology |
Volume | 30 |
Issue number | 2 |
DOIs | |
State | Published - 1988 |
Keywords
- Cushing's disease
- Intermediate lobe
- Monoclonal antibody
ASJC Scopus subject areas
- Clinical Neurology
- Surgery