Pitfalls in [18f]fdg PeT imaging in gynecological malignancies

Miguel Hernandez Pampaloni, Luca Facchetti, Lorenzo Nardo

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Gynecologic malignancies are the leading causes of cancer in women and they represent about 10 to 20% of all solid tumors. During the past few decades, technological advancements in the detection and staging have gained a pivotal role in all oncological processes, including the gynecological ones. Beyond ultrasound, computed tomography (CT) and magnetic resonance (MR) imaging that are conventionally used for anatomical imaging, [18f]fdg imaging and its hybrid further development as PeT/cT has become a crucial tool due of its ability to combine functional metabolic and anatomic information, and the ability to image the entire whole body in a single examination. Since the introduction of integrated hybrid PET/CT systems into clinical practice the accurate analysis of the images has detected a number of limitations and pitfalls. The purpose of this review was to describe in detail the different pitfalls related to the use of [18f]fdg PeT/cT in the gynecological malignancies, providing imaging examples and discussing possible ways to avoid misinterpretations.

Original languageEnglish (US)
Pages (from-to)124-138
Number of pages15
JournalQuarterly Journal of Nuclear Medicine and Molecular Imaging
Issue number2
StatePublished - Jan 1 2016
Externally publishedYes


  • Fluorodeoxyglucose F18
  • Pelvic neoplasms
  • Positron-emission tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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