Pilot study on gastric electrical stimulation on surgery-associated gastroparesis: Long-term outcome

Benton Oubre, Jean Luo, Amar Al-Juburi, Guy Voeller, Babajide Familoni, Thomas L. Abell

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Objectives: Patients with postgastric surgery gastroparesis are often unresponsive to conventional medical therapy. Gastric electrical stimulation (GES) with the use of high-frequency and low-energy neural stimulation is an approved technique for patients with idiopathic and diabetic gastroparesis. Methods: We hypothesized that GES would improve symptoms, health resource utilization, and gastric emptying in six patients with postsurgical gastroparesis from a variety of surgical procedures. Patients were evaluated by means of the following criteria: symptoms, health-related quality of life, and gastric emptying tests at baseline over time. Results: All patients noted improvements after device implantation for up to 46 months: the frequency score for weekly vomiting went from a baseline of 3.2 down to 0.4 immediately after treatment before settling at 1.4 by the long-term follow up. Total gastrointestinal symptom score went from 36.5 at baseline down to 12.3 before settling at 20.5 at long-term follow up. Improvements were also seen in health-related quality of life and solid and liquid gastric emptying. Conclusions: We conclude that GES is associated with clinical improvements in this group of patients with either postsurgical or surgery-associated gastroparesis. This pilot study with long-term outcomes offers evidence for a new therapy for otherwise refractory patients with gastroparesis associated with previous surgery.

Original languageEnglish (US)
Pages (from-to)693-697
Number of pages5
JournalSouthern Medical Journal
Volume98
Issue number7
DOIs
StatePublished - Jul 2005
Externally publishedYes

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Keywords

  • Electrical stimulation
  • Gastroparesis
  • Postgastrectomy syndromes

ASJC Scopus subject areas

  • Medicine(all)

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