Abstract
Purpose: To assess a 3D radial balanced steady-state free precession (SSFP) technique that provides submillimeter isotropic resolution and inherently registered fat and water image volumes in comparison to conventional T2-weighted RARE imaging for lesion characterization in breast magnetic resonance imaging (MRI). Materials and Methods: 3D projection SSFP (3DPR-SSFP) combines a dual half-echo radial k-space trajectory with a linear combination fat/water separation technique (linear combination SSFP). A pilot study was performed in 20 patients to assess fat suppression and depiction of lesion morphology using 3DPR-SSFP. For all patients fat suppression was measured for the 3DPR-SSFP image volumes and depiction of lesion morphology was compared against corresponding T2-weighted fast spin echo (FSE) datasets for 15 lesions in 11 patients. Results: The isotropic 0.63 mm resolution of the 3DPRSSFP sequence demonstrated improved depiction of lesion morphology in comparison to FSE. The 3DPR-SSFP fat and water datasets were available in a 5-minute scan time while average fat suppression with 3DPR-SSFP was 71% across all 20 patients. Conclusion: 3DPR-SSFP has the potential to improve the lesion characterization information available in breast MRI, particularly in comparison to conventional FSE. A larger study is warranted to quantify the effect of 3DPRSSFP on specificity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 135-144 |
| Number of pages | 10 |
| Journal | Journal of Magnetic Resonance Imaging |
| Volume | 30 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 1 2009 |
| Externally published | Yes |
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Keywords
- Breast imaging
- bSSFP
- Cancer imaging
- LC-SSFP
- Radial acquisition
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Pilot study of improved lesion characterization in breast MRI using a 3D radial balanced SSFP technique with isotropic resolution and efficient fat-water separation. / Moran, Catherine J.; Kelcz, Frederick; Jung, Youngkyoo; Brodsky, Ethan K.; Fain, Sean B.; Block, Walter F.
In: Journal of Magnetic Resonance Imaging, Vol. 30, No. 1, 01.07.2009, p. 135-144.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pilot study of improved lesion characterization in breast MRI using a 3D radial balanced SSFP technique with isotropic resolution and efficient fat-water separation
AU - Moran, Catherine J.
AU - Kelcz, Frederick
AU - Jung, Youngkyoo
AU - Brodsky, Ethan K.
AU - Fain, Sean B.
AU - Block, Walter F.
PY - 2009/7/1
Y1 - 2009/7/1
N2 - Purpose: To assess a 3D radial balanced steady-state free precession (SSFP) technique that provides submillimeter isotropic resolution and inherently registered fat and water image volumes in comparison to conventional T2-weighted RARE imaging for lesion characterization in breast magnetic resonance imaging (MRI). Materials and Methods: 3D projection SSFP (3DPR-SSFP) combines a dual half-echo radial k-space trajectory with a linear combination fat/water separation technique (linear combination SSFP). A pilot study was performed in 20 patients to assess fat suppression and depiction of lesion morphology using 3DPR-SSFP. For all patients fat suppression was measured for the 3DPR-SSFP image volumes and depiction of lesion morphology was compared against corresponding T2-weighted fast spin echo (FSE) datasets for 15 lesions in 11 patients. Results: The isotropic 0.63 mm resolution of the 3DPRSSFP sequence demonstrated improved depiction of lesion morphology in comparison to FSE. The 3DPR-SSFP fat and water datasets were available in a 5-minute scan time while average fat suppression with 3DPR-SSFP was 71% across all 20 patients. Conclusion: 3DPR-SSFP has the potential to improve the lesion characterization information available in breast MRI, particularly in comparison to conventional FSE. A larger study is warranted to quantify the effect of 3DPRSSFP on specificity.
AB - Purpose: To assess a 3D radial balanced steady-state free precession (SSFP) technique that provides submillimeter isotropic resolution and inherently registered fat and water image volumes in comparison to conventional T2-weighted RARE imaging for lesion characterization in breast magnetic resonance imaging (MRI). Materials and Methods: 3D projection SSFP (3DPR-SSFP) combines a dual half-echo radial k-space trajectory with a linear combination fat/water separation technique (linear combination SSFP). A pilot study was performed in 20 patients to assess fat suppression and depiction of lesion morphology using 3DPR-SSFP. For all patients fat suppression was measured for the 3DPR-SSFP image volumes and depiction of lesion morphology was compared against corresponding T2-weighted fast spin echo (FSE) datasets for 15 lesions in 11 patients. Results: The isotropic 0.63 mm resolution of the 3DPRSSFP sequence demonstrated improved depiction of lesion morphology in comparison to FSE. The 3DPR-SSFP fat and water datasets were available in a 5-minute scan time while average fat suppression with 3DPR-SSFP was 71% across all 20 patients. Conclusion: 3DPR-SSFP has the potential to improve the lesion characterization information available in breast MRI, particularly in comparison to conventional FSE. A larger study is warranted to quantify the effect of 3DPRSSFP on specificity.
KW - Breast imaging
KW - bSSFP
KW - Cancer imaging
KW - LC-SSFP
KW - Radial acquisition
UR - http://www.scopus.com/inward/record.url?scp=67650046404&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67650046404&partnerID=8YFLogxK
U2 - 10.1002/jmri.21807
DO - 10.1002/jmri.21807
M3 - Article
C2 - 19557728
AN - SCOPUS:67650046404
VL - 30
SP - 135
EP - 144
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
SN - 1053-1807
IS - 1
ER -