Physical activity and self-reported symptoms of insomnia, restless legs syndrome, and depression: The comprehensive dialysis study

Shuchi Anand, Kirsten L. Johansen, Barbara Grimes, George Kaysen, Lorien Dalrymple, Nancy G. Kutner, Glenn M. Chertow

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Symptoms of sleep and mood disturbances are common among patients on dialysis and are associated with significant decrements in survival and health-related quality of life. We used data from the Comprehensive Dialysis Study (CDS) to examine the association of self-reported physical activity with self-reported symptoms of insomnia, restless legs syndrome (RLS), and depression in patients new to dialysis. The CDS collected data on physical activity, functional status, and health-related quality of life from 1678 patients on either peritoneal (n=169) or hemodialysis (n=1509). The Human Activity Profile was used to measure self-reported physical activity. Symptoms were elicited in the following manner: insomnia using three questions designed to capture difficulty in initiating or maintaining sleep, RLS using three questions based on the National Institutes of Health workshop, and depression using the two-item Patient Health Questionnaire. We obtained data on symptoms of insomnia and depression for 1636, and on symptoms of RLS for 1622 (>98%) patients. Of these, 863 (53%) reported one of three insomnia symptoms as occurring at a persistent frequency. Symptoms of RLS and depression occurred in 477 (29%) and 451 (28%) of patients, respectively. The Adjusted Activity Score of the Human Activity Profile was inversely correlated with all three conditions in models adjusting for demographics, comorbid conditions, and laboratory variables. Sleep and mood disturbances were commonly reported in our large, diverse cohort of patients new to dialysis. Patients who reported lower levels of physical activity were more likely to report symptoms of insomnia, RLS, and depression. Hemodialysis International

Original languageEnglish (US)
Pages (from-to)50-58
Number of pages9
JournalHemodialysis International
Volume17
Issue number1
DOIs
StatePublished - Jan 2013

Fingerprint

Restless Legs Syndrome
Sleep Initiation and Maintenance Disorders
Dialysis
Exercise
Depression
Sleep
Human Activities
Renal Dialysis
Quality of Life
National Institutes of Health (U.S.)
Demography
Education
Survival
Health

Keywords

  • Cohort study
  • Depression
  • Dialysis
  • Insomnia
  • Physical activity
  • Restless leg syndrome

ASJC Scopus subject areas

  • Hematology
  • Nephrology

Cite this

Physical activity and self-reported symptoms of insomnia, restless legs syndrome, and depression : The comprehensive dialysis study. / Anand, Shuchi; Johansen, Kirsten L.; Grimes, Barbara; Kaysen, George; Dalrymple, Lorien; Kutner, Nancy G.; Chertow, Glenn M.

In: Hemodialysis International, Vol. 17, No. 1, 01.2013, p. 50-58.

Research output: Contribution to journalArticle

Anand, Shuchi ; Johansen, Kirsten L. ; Grimes, Barbara ; Kaysen, George ; Dalrymple, Lorien ; Kutner, Nancy G. ; Chertow, Glenn M. / Physical activity and self-reported symptoms of insomnia, restless legs syndrome, and depression : The comprehensive dialysis study. In: Hemodialysis International. 2013 ; Vol. 17, No. 1. pp. 50-58.
@article{38debd08ba6446a4bd78caa04db40f4e,
title = "Physical activity and self-reported symptoms of insomnia, restless legs syndrome, and depression: The comprehensive dialysis study",
abstract = "Symptoms of sleep and mood disturbances are common among patients on dialysis and are associated with significant decrements in survival and health-related quality of life. We used data from the Comprehensive Dialysis Study (CDS) to examine the association of self-reported physical activity with self-reported symptoms of insomnia, restless legs syndrome (RLS), and depression in patients new to dialysis. The CDS collected data on physical activity, functional status, and health-related quality of life from 1678 patients on either peritoneal (n=169) or hemodialysis (n=1509). The Human Activity Profile was used to measure self-reported physical activity. Symptoms were elicited in the following manner: insomnia using three questions designed to capture difficulty in initiating or maintaining sleep, RLS using three questions based on the National Institutes of Health workshop, and depression using the two-item Patient Health Questionnaire. We obtained data on symptoms of insomnia and depression for 1636, and on symptoms of RLS for 1622 (>98{\%}) patients. Of these, 863 (53{\%}) reported one of three insomnia symptoms as occurring at a persistent frequency. Symptoms of RLS and depression occurred in 477 (29{\%}) and 451 (28{\%}) of patients, respectively. The Adjusted Activity Score of the Human Activity Profile was inversely correlated with all three conditions in models adjusting for demographics, comorbid conditions, and laboratory variables. Sleep and mood disturbances were commonly reported in our large, diverse cohort of patients new to dialysis. Patients who reported lower levels of physical activity were more likely to report symptoms of insomnia, RLS, and depression. Hemodialysis International",
keywords = "Cohort study, Depression, Dialysis, Insomnia, Physical activity, Restless leg syndrome",
author = "Shuchi Anand and Johansen, {Kirsten L.} and Barbara Grimes and George Kaysen and Lorien Dalrymple and Kutner, {Nancy G.} and Chertow, {Glenn M.}",
year = "2013",
month = "1",
doi = "10.1111/j.1542-4758.2012.00726.x",
language = "English (US)",
volume = "17",
pages = "50--58",
journal = "Hemodialysis International",
issn = "1492-7535",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Physical activity and self-reported symptoms of insomnia, restless legs syndrome, and depression

T2 - The comprehensive dialysis study

AU - Anand, Shuchi

AU - Johansen, Kirsten L.

AU - Grimes, Barbara

AU - Kaysen, George

AU - Dalrymple, Lorien

AU - Kutner, Nancy G.

AU - Chertow, Glenn M.

PY - 2013/1

Y1 - 2013/1

N2 - Symptoms of sleep and mood disturbances are common among patients on dialysis and are associated with significant decrements in survival and health-related quality of life. We used data from the Comprehensive Dialysis Study (CDS) to examine the association of self-reported physical activity with self-reported symptoms of insomnia, restless legs syndrome (RLS), and depression in patients new to dialysis. The CDS collected data on physical activity, functional status, and health-related quality of life from 1678 patients on either peritoneal (n=169) or hemodialysis (n=1509). The Human Activity Profile was used to measure self-reported physical activity. Symptoms were elicited in the following manner: insomnia using three questions designed to capture difficulty in initiating or maintaining sleep, RLS using three questions based on the National Institutes of Health workshop, and depression using the two-item Patient Health Questionnaire. We obtained data on symptoms of insomnia and depression for 1636, and on symptoms of RLS for 1622 (>98%) patients. Of these, 863 (53%) reported one of three insomnia symptoms as occurring at a persistent frequency. Symptoms of RLS and depression occurred in 477 (29%) and 451 (28%) of patients, respectively. The Adjusted Activity Score of the Human Activity Profile was inversely correlated with all three conditions in models adjusting for demographics, comorbid conditions, and laboratory variables. Sleep and mood disturbances were commonly reported in our large, diverse cohort of patients new to dialysis. Patients who reported lower levels of physical activity were more likely to report symptoms of insomnia, RLS, and depression. Hemodialysis International

AB - Symptoms of sleep and mood disturbances are common among patients on dialysis and are associated with significant decrements in survival and health-related quality of life. We used data from the Comprehensive Dialysis Study (CDS) to examine the association of self-reported physical activity with self-reported symptoms of insomnia, restless legs syndrome (RLS), and depression in patients new to dialysis. The CDS collected data on physical activity, functional status, and health-related quality of life from 1678 patients on either peritoneal (n=169) or hemodialysis (n=1509). The Human Activity Profile was used to measure self-reported physical activity. Symptoms were elicited in the following manner: insomnia using three questions designed to capture difficulty in initiating or maintaining sleep, RLS using three questions based on the National Institutes of Health workshop, and depression using the two-item Patient Health Questionnaire. We obtained data on symptoms of insomnia and depression for 1636, and on symptoms of RLS for 1622 (>98%) patients. Of these, 863 (53%) reported one of three insomnia symptoms as occurring at a persistent frequency. Symptoms of RLS and depression occurred in 477 (29%) and 451 (28%) of patients, respectively. The Adjusted Activity Score of the Human Activity Profile was inversely correlated with all three conditions in models adjusting for demographics, comorbid conditions, and laboratory variables. Sleep and mood disturbances were commonly reported in our large, diverse cohort of patients new to dialysis. Patients who reported lower levels of physical activity were more likely to report symptoms of insomnia, RLS, and depression. Hemodialysis International

KW - Cohort study

KW - Depression

KW - Dialysis

KW - Insomnia

KW - Physical activity

KW - Restless leg syndrome

UR - http://www.scopus.com/inward/record.url?scp=84872659652&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84872659652&partnerID=8YFLogxK

U2 - 10.1111/j.1542-4758.2012.00726.x

DO - 10.1111/j.1542-4758.2012.00726.x

M3 - Article

C2 - 22812496

AN - SCOPUS:84872659652

VL - 17

SP - 50

EP - 58

JO - Hemodialysis International

JF - Hemodialysis International

SN - 1492-7535

IS - 1

ER -