Physical activity and incidence of postmenopausal breast cancer

Derek B. Moore, Aaron R. Folsom, Pamela J. Mink, Ching Ping Hong, Kristin E. Anderson, Lawrence H. Kushi

Research output: Contribution to journalArticlepeer-review

66 Scopus citations


Whether physical activity reduces the risk of postmenopausal breast cancer is uncertain; few studies have addressed this issue. We examined the association of leisure physical activity with breast cancer incidence among 37,105 postmenopausal participants in the Iowa Women's Health Study. Women reporting the highest level of physical activity at baseline compared with women with the lowest level of activity had an age-adjusted relative risk of breast cancer of 0.92 (95% confidence interval = 0.80-1.05). Women reporting any regular leisure-time physical activity had a relative risk of 0.97 (95% confidence interval = 0.87-1.08) compared with those reporting no such regular physical activity. Adjustment for potential confounders did not appreciably alter the findings. There is little evidence from this study that physical activity later in life is associated to any appreciable extent with breast cancer incidence.

Original languageEnglish (US)
Pages (from-to)292-296
Number of pages5
Issue number3
StatePublished - May 2000
Externally publishedYes


  • Breast cancer
  • Cohort study
  • Physical activity
  • Postmenopausal women

ASJC Scopus subject areas

  • Epidemiology


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