Photosensitised conversion of cytosine into uracil derivatives in the presence of mercaptans

Nien Chu C Yang; Renji Okazaki; Fu-Tong Liu

doi:10.1039/C39740000462

Photosensitised conversion of cytosine into uracil derivatives in the presence of mercaptans

Nien Chu C Yang, Renji Okazaki, Fu-Tong Liu

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Acetone sensitized photochemical reaction between cytosine and cysteine in water yields 5,6-dihydro-uracil (72%), 5-S-cysteinyl-5,6-dihydrouracil (24%), and uracil (2.2%), suggesting that radiation may cause not only crosslinking of proteins to nucleic acids but also base modifications.

Original language	English (US)
Pages (from-to)	462-463
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	12
DOIs	https://doi.org/10.1039/C39740000462
State	Published - 1974
Externally published	Yes

ASJC Scopus subject areas

Molecular Medicine

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title = "Photosensitised conversion of cytosine into uracil derivatives in the presence of mercaptans",

abstract = "Acetone sensitized photochemical reaction between cytosine and cysteine in water yields 5,6-dihydro-uracil (72%), 5-S-cysteinyl-5,6-dihydrouracil (24%), and uracil (2.2%), suggesting that radiation may cause not only crosslinking of proteins to nucleic acids but also base modifications.",

author = "Yang, {Nien Chu C} and Renji Okazaki and Fu-Tong Liu",

year = "1974",

doi = "10.1039/C39740000462",

language = "English (US)",

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journal = "Chemical Communications",

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AB - Acetone sensitized photochemical reaction between cytosine and cysteine in water yields 5,6-dihydro-uracil (72%), 5-S-cysteinyl-5,6-dihydrouracil (24%), and uracil (2.2%), suggesting that radiation may cause not only crosslinking of proteins to nucleic acids but also base modifications.

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