Abstract
Brown adipose tissue is a major thermogenic effector of cold-induced nonshivering thermogenesis. Previous studies indicate that melatonin and/or short photo-period are involved in the increase in brown fat deposition seen in certain cold-acclimated rodents. The present study was undertaken, in part, to determine whether the pineal is a necessary component in the cold-induced increase in thermogenic capacity characteristic of the cold-acclimated laboratory rat. Under a 12L:12D light cycle, pinealectomized rats did not differ from sham-operated rats in their ability to increase brown fat deposition in the cold (5 °C). Moreover, in a subsequent set of experiments performed at 9 °C, intact rats maintained at a short photoperiod (9L:15D) exhibited the same degree of brown fat hypertrophy/hyperplasia as did those kept at a long photoperiod (15L:9D). These data thus indicate that: (a) the intact pineal is not necessary for the cold-induced increase in brown adipose tissue occurring in the cold-acclimated rat; and (b) photoperiod does not significantly modulate the magnitude of this increase.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 100-105 |
| Number of pages | 6 |
| Journal | Cryobiology |
| Volume | 20 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1983 |
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ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
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Photoperiod and pinealectomy do not affect cold-induced deposition of brown adipose tissue in the long-evans rat. / Kott, K. S.; Horwitz, Barbara A.
In: Cryobiology, Vol. 20, No. 1, 1983, p. 100-105.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Photoperiod and pinealectomy do not affect cold-induced deposition of brown adipose tissue in the long-evans rat
AU - Kott, K. S.
AU - Horwitz, Barbara A
PY - 1983
Y1 - 1983
N2 - Brown adipose tissue is a major thermogenic effector of cold-induced nonshivering thermogenesis. Previous studies indicate that melatonin and/or short photo-period are involved in the increase in brown fat deposition seen in certain cold-acclimated rodents. The present study was undertaken, in part, to determine whether the pineal is a necessary component in the cold-induced increase in thermogenic capacity characteristic of the cold-acclimated laboratory rat. Under a 12L:12D light cycle, pinealectomized rats did not differ from sham-operated rats in their ability to increase brown fat deposition in the cold (5 °C). Moreover, in a subsequent set of experiments performed at 9 °C, intact rats maintained at a short photoperiod (9L:15D) exhibited the same degree of brown fat hypertrophy/hyperplasia as did those kept at a long photoperiod (15L:9D). These data thus indicate that: (a) the intact pineal is not necessary for the cold-induced increase in brown adipose tissue occurring in the cold-acclimated rat; and (b) photoperiod does not significantly modulate the magnitude of this increase.
AB - Brown adipose tissue is a major thermogenic effector of cold-induced nonshivering thermogenesis. Previous studies indicate that melatonin and/or short photo-period are involved in the increase in brown fat deposition seen in certain cold-acclimated rodents. The present study was undertaken, in part, to determine whether the pineal is a necessary component in the cold-induced increase in thermogenic capacity characteristic of the cold-acclimated laboratory rat. Under a 12L:12D light cycle, pinealectomized rats did not differ from sham-operated rats in their ability to increase brown fat deposition in the cold (5 °C). Moreover, in a subsequent set of experiments performed at 9 °C, intact rats maintained at a short photoperiod (9L:15D) exhibited the same degree of brown fat hypertrophy/hyperplasia as did those kept at a long photoperiod (15L:9D). These data thus indicate that: (a) the intact pineal is not necessary for the cold-induced increase in brown adipose tissue occurring in the cold-acclimated rat; and (b) photoperiod does not significantly modulate the magnitude of this increase.
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U2 - 10.1016/0011-2240(83)90064-0
DO - 10.1016/0011-2240(83)90064-0
M3 - Article
C2 - 6831906
AN - SCOPUS:0020679321
VL - 20
SP - 100
EP - 105
JO - Cryobiology
JF - Cryobiology
SN - 0011-2240
IS - 1
ER -