Photocyclisation of haloacetyl tryptophan derivatives

Mark Mascal, Christopher J. Moody

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Irradiation of dichioroacetyl tryptophan methyl ester gives, after addition of a nucleophile in work-up, the 7-substituted pyrrolobenzazocines (7); similar cyclisation of the tryptophan derivative (11) gives the pyrrolobenzazocine (12), a compound related to serotobenine.

Original languageEnglish (US)
Pages (from-to)587-588
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number9
DOIs
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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