Photocyclisation of haloacetyl tryptophan derivatives

Mark Mascal, Christopher J. Moody

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Irradiation of dichioroacetyl tryptophan methyl ester gives, after addition of a nucleophile in work-up, the 7-substituted pyrrolobenzazocines (7); similar cyclisation of the tryptophan derivative (11) gives the pyrrolobenzazocine (12), a compound related to serotobenine.

Original languageEnglish (US)
Pages (from-to)587-588
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number9
DOIs
StatePublished - 1988
Externally publishedYes

Fingerprint

Nucleophiles
Cyclization
Tryptophan
Esters
Irradiation
Derivatives
serotobenine
tryptophan methyl ester

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Photocyclisation of haloacetyl tryptophan derivatives. / Mascal, Mark; Moody, Christopher J.

In: Journal of the Chemical Society, Chemical Communications, No. 9, 1988, p. 587-588.

Research output: Contribution to journalArticle

Mascal, Mark ; Moody, Christopher J. / Photocyclisation of haloacetyl tryptophan derivatives. In: Journal of the Chemical Society, Chemical Communications. 1988 ; No. 9. pp. 587-588.
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