Phimosis with preputial fissures as a predictor of undiagnosed type 2 diabetes in adults

Yun Ching Huang, Yao Kuang Huang, Chih Shou Chen, Alan W Shindel, Ching Fang Wu, Jian Hui Lin, Kuo Hsiung Chiu, Tzu Hsin Yang, Chung Sheng Shi

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Diabetes is usually asymptomatic in its early stage. Early diagnosis may improve outcomes by enabling initiation of treatment before end organ damage has progressed. The aim of this study was to determine whether the clinical sign of phimosis with preputial fissures is predictive of type 2 diabetes in patients not previously diagnosed with diabetes. Twenty-eight patients with acquired phimosis and preputial fissures were collected prospectively. Twenty-eight controls with acquired phimosis without preputial fissures were selected. Statistically significant differences were found in body mass index, random plasma glucose, glucosuria and glycosylated haemoglobin levels, but not in age, family history of diabetes, hypertension and classical hyperglycaemic symptoms. Diabetes was confirmed in all 28 patients in the preputial fissures group, but only 2 (7.1%) patients in the non-preputial fissures group (p < 0.0001). In conclusion, phimosis with preputial fissures may be a specific sign of undiagnosed diabetes mellitus.

Original languageEnglish (US)
Pages (from-to)377-380
Number of pages4
JournalActa Dermato-Venereologica
Issue number3
StatePublished - Mar 1 2016


  • Diabetes
  • Phimosis
  • Preputial fissure

ASJC Scopus subject areas

  • Dermatology


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