Phenylsulfonyl as a directing group for nitrile oxide cycloadditions and mCPBA epoxidations

Jeffrey D. Butler, Michael B. Donald, Zhensheng Ding, James C. Fettinger, Mark J. Kurth

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

An unexpected selectivity trend in the nitrile oxide cycloaddition and epoxidation reactions of 4,4-disubstituted cyclopentenes is reported. A variety of facially distinct, 'X-' and 'Y-substituted' cyclopentenes were investigated.

Original languageEnglish (US)
Pages (from-to)5110-5112
Number of pages3
JournalTetrahedron Letters
Volume50
Issue number36
DOIs
StatePublished - Sep 9 2009

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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    Butler, J. D., Donald, M. B., Ding, Z., Fettinger, J. C., & Kurth, M. J. (2009). Phenylsulfonyl as a directing group for nitrile oxide cycloadditions and mCPBA epoxidations. Tetrahedron Letters, 50(36), 5110-5112. https://doi.org/10.1016/j.tetlet.2009.06.100