Phase-transition based transduction in a biosensor

J. F. Bardeau, A. S. Eberhardt, R. M. Nyquist, A. N. Parikh, A. P. Shreve, B. I. Swanson

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Shifts in the main phase transition temperatures caused by a highly specific, protein-receptor interaction in a hybrid bilayer architecture are probed utilizing temperature programmed infrared vibrational spectroscopy. The specific case of cholera toxin attachment to glycolipid receptors embedded in a phospholipid outer layer at a hydrophobized silicon surface is investigated. Potential applications of the approach as a signal amplification method in biosensors will be discussed.

Original languageEnglish (US)
Pages (from-to)1452-1453
Number of pages2
JournalSynthetic Metals
Volume102
Issue number1-3
DOIs
StatePublished - Jun 1999
Externally publishedYes

Fingerprint

Vibrational spectroscopy
Cholera Toxin
Phospholipids
Silicon
bioinstrumentation
Biosensors
Superconducting transition temperature
Amplification
Infrared spectroscopy
cholera
Phase transitions
Proteins
attachment
transition temperature
proteins
Temperature
shift
silicon
spectroscopy
interactions

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Materials Chemistry
  • Polymers and Plastics

Cite this

Bardeau, J. F., Eberhardt, A. S., Nyquist, R. M., Parikh, A. N., Shreve, A. P., & Swanson, B. I. (1999). Phase-transition based transduction in a biosensor. Synthetic Metals, 102(1-3), 1452-1453. https://doi.org/10.1016/S0379-6779(98)00509-8

Phase-transition based transduction in a biosensor. / Bardeau, J. F.; Eberhardt, A. S.; Nyquist, R. M.; Parikh, A. N.; Shreve, A. P.; Swanson, B. I.

In: Synthetic Metals, Vol. 102, No. 1-3, 06.1999, p. 1452-1453.

Research output: Contribution to journalArticle

Bardeau, JF, Eberhardt, AS, Nyquist, RM, Parikh, AN, Shreve, AP & Swanson, BI 1999, 'Phase-transition based transduction in a biosensor', Synthetic Metals, vol. 102, no. 1-3, pp. 1452-1453. https://doi.org/10.1016/S0379-6779(98)00509-8
Bardeau JF, Eberhardt AS, Nyquist RM, Parikh AN, Shreve AP, Swanson BI. Phase-transition based transduction in a biosensor. Synthetic Metals. 1999 Jun;102(1-3):1452-1453. https://doi.org/10.1016/S0379-6779(98)00509-8
Bardeau, J. F. ; Eberhardt, A. S. ; Nyquist, R. M. ; Parikh, A. N. ; Shreve, A. P. ; Swanson, B. I. / Phase-transition based transduction in a biosensor. In: Synthetic Metals. 1999 ; Vol. 102, No. 1-3. pp. 1452-1453.
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