Acute severe asthma calls for aggressive and early therapy of a multifaceted and all-inclusive approach (Fig.2). Therapy merely begins in the ED and manifold distinct issues need to find consideration during ongoing hospital care. Currently, β-agonists, anti-cholinergic agents, and corticosteroids remain the mainstay of therapy. Methylxanthines and magnesium may find consideration in carefully selected patients. Multiple new therapeutic avenues, such as the anti-leukotriene drugs, seem promising and future studies will hopefully extend our armamentarium against life threatening complication of a common disease. Asthma education begun in the hospital may provide the platform for preventing severe acute exacerbations and hospitalization.
ASJC Scopus subject areas
- Immunology and Allergy