Pharmacologic approach to management of agitation associated with dementia

M. E. Kunik, S. C. Yudofsky, J. M. Silver, Robert E Hales

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Dementia is a complex syndrome associated with cognitive impairment, personality change, and behavioral disturbance. Behavioral symptoms frequently present the greatest challenge for caregivers and are often the determining factor in institutional placement. Determining the need for pharmacologic treatment of an agitated patient requires considering the full range of biopsychosocial variables and ultimately involves assessing the risks and benefits of the medications selected for the patient. In this article, the phenomenology of agitation is reviewed along with the pharmacologic treatment of agitation in patients with dementia, including the use of benzodiazepines, neuroleptics, β-adrenergic-blocking agents, serotonergic agents, carbamazepine, and lithium.

Original languageEnglish (US)
Pages (from-to)13-17
Number of pages5
JournalJournal of Clinical Psychiatry
Volume55
Issue number2 SUPPL.
StatePublished - 1994
Externally publishedYes

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Dementia
Serotonin Agents
Behavioral Symptoms
Adrenergic Antagonists
Carbamazepine
Benzodiazepines
Lithium
Caregivers
Antipsychotic Agents
Personality
Therapeutics
Cognitive Dysfunction

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

Pharmacologic approach to management of agitation associated with dementia. / Kunik, M. E.; Yudofsky, S. C.; Silver, J. M.; Hales, Robert E.

In: Journal of Clinical Psychiatry, Vol. 55, No. 2 SUPPL., 1994, p. 13-17.

Research output: Contribution to journalArticle

Kunik, ME, Yudofsky, SC, Silver, JM & Hales, RE 1994, 'Pharmacologic approach to management of agitation associated with dementia', Journal of Clinical Psychiatry, vol. 55, no. 2 SUPPL., pp. 13-17.
Kunik, M. E. ; Yudofsky, S. C. ; Silver, J. M. ; Hales, Robert E. / Pharmacologic approach to management of agitation associated with dementia. In: Journal of Clinical Psychiatry. 1994 ; Vol. 55, No. 2 SUPPL. pp. 13-17.
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