PET/SPECT/MRI multimodal nanoparticles

Tang Tang, Joel Garcia, Angelique Y. Louie

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Hybrid imaging is an emerging technology that typically fuses a combination of high-sensitivity, nuclear imaging techniques, such as positron emission tomography (PET) or single-photon emission computed tomography (SPECT), with high-resolution, anatomical imaging using computed tomography (CT) or magnetic resonance imaging (MRI). CT was the first partner in hybrid imaging systems and modern interest has focused on development of MRI hybrids. To fully exploit the benefits of hybrid imaging technology, researchers have been investigating the use of radiolabeled and paramagnetic, nanoparticle-based probes to allow simultaneous imaging with PET/SPECT and MRI for a variety of applications including targeted tumor imaging, stem cell tracking, and monitoring of response to therapy. This chapter provides an overview of unique designs for nanoparticle-based SPECT/MRI and PET/MRI probes, and their imaging applications, reported in the period of 2010-2015.

Original languageEnglish (US)
Title of host publicationDesign and Applications of Nanoparticles in Biomedical Imaging
PublisherSpringer International Publishing
Pages205-228
Number of pages24
ISBN (Electronic)9783319421698
ISBN (Print)9783319421674
DOIs
StatePublished - Jan 1 2016

Keywords

  • MRI
  • Multimodal imaging
  • Nanoparticles
  • PET
  • SPECT

ASJC Scopus subject areas

  • Medicine(all)
  • Health Professions(all)
  • Engineering(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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    Tang, T., Garcia, J., & Louie, A. Y. (2016). PET/SPECT/MRI multimodal nanoparticles. In Design and Applications of Nanoparticles in Biomedical Imaging (pp. 205-228). Springer International Publishing. https://doi.org/10.1007/978-3-319-42169-8_10