Perspective: Fundamental and clinical concepts on stem cell homing and engraftment: A journey to niches and beyond

Peter J. Quesenberry, Gerald Colvin, Mehrdad Abedi

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

In many ways, the homing of hematopoietic stem cells to bone marrow and other tissues defines these cells and their immediate and long-term fates Once homed, an inevitable series of proliferative and differentiative events presumptively follows. These comments, of course, hold for both homing to marrow, or alternatively, to other nonmarrow tissues. In this review, we will specifically focus on homing and engraftment to bone marrow because this is the best-studied and clinically applicable system.

Original languageEnglish (US)
Pages (from-to)9-19
Number of pages11
JournalExperimental Hematology
Volume33
Issue number1
DOIs
StatePublished - Jan 2005
Externally publishedYes

Fingerprint

Stem Cells
Bone Marrow
Hematopoietic Stem Cells

ASJC Scopus subject areas

  • Cancer Research
  • Cell Biology
  • Genetics
  • Hematology
  • Oncology
  • Transplantation

Cite this

Perspective : Fundamental and clinical concepts on stem cell homing and engraftment: A journey to niches and beyond. / Quesenberry, Peter J.; Colvin, Gerald; Abedi, Mehrdad.

In: Experimental Hematology, Vol. 33, No. 1, 01.2005, p. 9-19.

Research output: Contribution to journalArticle

@article{115e9b9818d14c5194521693dc0d7edd,
title = "Perspective: Fundamental and clinical concepts on stem cell homing and engraftment: A journey to niches and beyond",
abstract = "In many ways, the homing of hematopoietic stem cells to bone marrow and other tissues defines these cells and their immediate and long-term fates Once homed, an inevitable series of proliferative and differentiative events presumptively follows. These comments, of course, hold for both homing to marrow, or alternatively, to other nonmarrow tissues. In this review, we will specifically focus on homing and engraftment to bone marrow because this is the best-studied and clinically applicable system.",
author = "Quesenberry, {Peter J.} and Gerald Colvin and Mehrdad Abedi",
year = "2005",
month = "1",
doi = "10.1016/j.exphem.2004.10.012",
language = "English (US)",
volume = "33",
pages = "9--19",
journal = "Experimental Hematology",
issn = "0301-472X",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Perspective

T2 - Fundamental and clinical concepts on stem cell homing and engraftment: A journey to niches and beyond

AU - Quesenberry, Peter J.

AU - Colvin, Gerald

AU - Abedi, Mehrdad

PY - 2005/1

Y1 - 2005/1

N2 - In many ways, the homing of hematopoietic stem cells to bone marrow and other tissues defines these cells and their immediate and long-term fates Once homed, an inevitable series of proliferative and differentiative events presumptively follows. These comments, of course, hold for both homing to marrow, or alternatively, to other nonmarrow tissues. In this review, we will specifically focus on homing and engraftment to bone marrow because this is the best-studied and clinically applicable system.

AB - In many ways, the homing of hematopoietic stem cells to bone marrow and other tissues defines these cells and their immediate and long-term fates Once homed, an inevitable series of proliferative and differentiative events presumptively follows. These comments, of course, hold for both homing to marrow, or alternatively, to other nonmarrow tissues. In this review, we will specifically focus on homing and engraftment to bone marrow because this is the best-studied and clinically applicable system.

UR - http://www.scopus.com/inward/record.url?scp=12344324650&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=12344324650&partnerID=8YFLogxK

U2 - 10.1016/j.exphem.2004.10.012

DO - 10.1016/j.exphem.2004.10.012

M3 - Article

C2 - 15661393

AN - SCOPUS:12344324650

VL - 33

SP - 9

EP - 19

JO - Experimental Hematology

JF - Experimental Hematology

SN - 0301-472X

IS - 1

ER -