Persistent free-floating pelvic trophoblastic cysts following an interstitial ectopic pregnancy

Research output: Contribution to journalArticle

Abstract

Persistent trophoblast after ectopic pregnancy has been demonstrated at the surgical site or as peritoneal implants. A 37-year-old woman (G5P2) experienced persistently low levels of beta-human chorionic gonadotropin (hCG) after surgical treatment for an interstitial pregnancy. Evaluation for persistent trophoblast, gestational trophoblastic neoplasm and heterophilic antibodies was negative. After 15 months without resolution, she elected for hysterectomy. We found four smooth, freely floating avascular cysts intraoperatively; pathological evaluation identified the cysts as trophoblastic tissue. Serum beta-hCG resolved postoperatively and remained negative at 1 year. Our case demonstrates the novel finding of trophoblastic tissue existing as free-floating cysts in the peritoneal cavity. With appropriate suspicion, these cysts can be identified on radiologic investigation and removed laparoscopically.

Original languageEnglish (US)
Article numbere229732
JournalBMJ Case Reports
Volume12
Issue number8
DOIs
StatePublished - Aug 1 2019

Fingerprint

Ectopic Pregnancy
Cysts
Trophoblasts
Chorionic Gonadotropin
Gestational Trophoblastic Disease
Neoplasm Antibodies
Peritoneal Cavity
Hysterectomy
Interstitial Pregnancy
Serum
Therapeutics

Keywords

  • obstetrics and gynaecology
  • pregnancy
  • reproductive medicine

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Persistent free-floating pelvic trophoblastic cysts following an interstitial ectopic pregnancy. / Crawford, Kaitlin D.; Chen, Melissa; Hou, Melody; Creinin, Mitchell D.

In: BMJ Case Reports, Vol. 12, No. 8, e229732, 01.08.2019.

Research output: Contribution to journalArticle

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