Pernicious anemia in blacks. A study of 64 patients from Washington, D.C. and Johannesburg, South Africa

D. L. Solanki, R. J. Jacobson, Ralph Green, J. McKibbon, R. Berdoff

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

In a collaborative study from Washington, D.C., and Johannesburg, South Africa, the clinical, laboratory, and immunologic features of 64 black patients (25 male, 39 female) who had pernicious anemia were studied. Mean age at diagnosis was 53 ± 20 years (mean ± SD); 29.6% of the patients were under 40 years of age, and 14% were 30 years of age or younger. This suggests that there may be an earlier age of onset of pernicious anemia amongst blacks than the reported age incidence in whites. Serum anti-intrinsic factor blocking antibodies were found in 25 of 37 patients tested (67.5%). There was a significantly higher incidence of the antibody in women (85%) than in men (50%) (P<0.01).

Original languageEnglish (US)
Pages (from-to)96-99
Number of pages4
JournalAmerican Journal of Clinical Pathology
Volume75
Issue number1
StatePublished - 1981
Externally publishedYes

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Pernicious Anemia
South Africa
Intrinsic Factor
Blocking Antibodies
Incidence
Age of Onset
Antibodies
Serum

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Pernicious anemia in blacks. A study of 64 patients from Washington, D.C. and Johannesburg, South Africa. / Solanki, D. L.; Jacobson, R. J.; Green, Ralph; McKibbon, J.; Berdoff, R.

In: American Journal of Clinical Pathology, Vol. 75, No. 1, 1981, p. 96-99.

Research output: Contribution to journalArticle

Solanki, D. L. ; Jacobson, R. J. ; Green, Ralph ; McKibbon, J. ; Berdoff, R. / Pernicious anemia in blacks. A study of 64 patients from Washington, D.C. and Johannesburg, South Africa. In: American Journal of Clinical Pathology. 1981 ; Vol. 75, No. 1. pp. 96-99.
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