Abstract
In a collaborative study from Washington, D.C., and Johannesburg, South Africa, the clinical, laboratory, and immunologic features of 64 black patients (25 male, 39 female) who had pernicious anemia were studied. Mean age at diagnosis was 53 ± 20 years (mean ± SD); 29.6% of the patients were under 40 years of age, and 14% were 30 years of age or younger. This suggests that there may be an earlier age of onset of pernicious anemia amongst blacks than the reported age incidence in whites. Serum anti-intrinsic factor blocking antibodies were found in 25 of 37 patients tested (67.5%). There was a significantly higher incidence of the antibody in women (85%) than in men (50%) (P<0.01).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 96-99 |
| Number of pages | 4 |
| Journal | American Journal of Clinical Pathology |
| Volume | 75 |
| Issue number | 1 |
| State | Published - 1981 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pathology and Forensic Medicine
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Pernicious anemia in blacks. A study of 64 patients from Washington, D.C. and Johannesburg, South Africa. / Solanki, D. L.; Jacobson, R. J.; Green, Ralph; McKibbon, J.; Berdoff, R.
In: American Journal of Clinical Pathology, Vol. 75, No. 1, 1981, p. 96-99.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pernicious anemia in blacks. A study of 64 patients from Washington, D.C. and Johannesburg, South Africa
AU - Solanki, D. L.
AU - Jacobson, R. J.
AU - Green, Ralph
AU - McKibbon, J.
AU - Berdoff, R.
PY - 1981
Y1 - 1981
N2 - In a collaborative study from Washington, D.C., and Johannesburg, South Africa, the clinical, laboratory, and immunologic features of 64 black patients (25 male, 39 female) who had pernicious anemia were studied. Mean age at diagnosis was 53 ± 20 years (mean ± SD); 29.6% of the patients were under 40 years of age, and 14% were 30 years of age or younger. This suggests that there may be an earlier age of onset of pernicious anemia amongst blacks than the reported age incidence in whites. Serum anti-intrinsic factor blocking antibodies were found in 25 of 37 patients tested (67.5%). There was a significantly higher incidence of the antibody in women (85%) than in men (50%) (P<0.01).
AB - In a collaborative study from Washington, D.C., and Johannesburg, South Africa, the clinical, laboratory, and immunologic features of 64 black patients (25 male, 39 female) who had pernicious anemia were studied. Mean age at diagnosis was 53 ± 20 years (mean ± SD); 29.6% of the patients were under 40 years of age, and 14% were 30 years of age or younger. This suggests that there may be an earlier age of onset of pernicious anemia amongst blacks than the reported age incidence in whites. Serum anti-intrinsic factor blocking antibodies were found in 25 of 37 patients tested (67.5%). There was a significantly higher incidence of the antibody in women (85%) than in men (50%) (P<0.01).
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UR - http://www.scopus.com/inward/citedby.url?scp=0019482751&partnerID=8YFLogxK
M3 - Article
C2 - 7457436
AN - SCOPUS:0019482751
VL - 75
SP - 96
EP - 99
JO - American Journal of Clinical Pathology
JF - American Journal of Clinical Pathology
SN - 0002-9173
IS - 1
ER -