TY - JOUR
T1 - Permeate from cheese whey ultrafiltration is a source of milk oligosaccharides
AU - Barile, Daniela
AU - Tao, Nannan
AU - Lebrilla, Carlito B
AU - Coisson, Jean Daniel
AU - Arlorio, Marco
AU - German, J. Bruce
PY - 2009/9
Y1 - 2009/9
N2 - Previously undescribed oligosaccharides in bovine cheese whey permeate were characterized by a combination of nanoelectrospray Fourier transform ion cyclotron resonance (nESI-FTICR) mass spectrometry and matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance (MALDI-FTICR) mass spectrometry. Oligosaccharide composition was elucidated by collision-induced dissociation within the ICR cell. In addition to sialyllactose (the most abundant oligosaccharide in bovine colostrum), we identified 14 other oligosaccharides, half of which have the same composition of human milk oligosaccharides. These oligosaccharides could potentially be used as additives in infant formula and products for the pharmaceutical industry. Because whey permeate is a by-product from the production of whey protein concentrate (WPC) and is readily available, it is an attractive source of oligosaccharides for potential application in human nutrition.
AB - Previously undescribed oligosaccharides in bovine cheese whey permeate were characterized by a combination of nanoelectrospray Fourier transform ion cyclotron resonance (nESI-FTICR) mass spectrometry and matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance (MALDI-FTICR) mass spectrometry. Oligosaccharide composition was elucidated by collision-induced dissociation within the ICR cell. In addition to sialyllactose (the most abundant oligosaccharide in bovine colostrum), we identified 14 other oligosaccharides, half of which have the same composition of human milk oligosaccharides. These oligosaccharides could potentially be used as additives in infant formula and products for the pharmaceutical industry. Because whey permeate is a by-product from the production of whey protein concentrate (WPC) and is readily available, it is an attractive source of oligosaccharides for potential application in human nutrition.
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U2 - 10.1016/j.idairyj.2009.03.008
DO - 10.1016/j.idairyj.2009.03.008
M3 - Article
AN - SCOPUS:67349260397
VL - 19
SP - 524
EP - 530
JO - International Dairy Journal
JF - International Dairy Journal
SN - 0958-6946
IS - 9
ER -