Peritoneal Surface Disease Severity Score as a predictor of resectability in the treatment of peritoneal surface malignancies

William Yoon, Amer Alame, Richard Berri

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Background We evaluated the clinical utility of the Peritoneal Surface Disease Severity Score (PSDSS) as a preoperative predictor of resectability in the treatment of peritoneal surface malignancies. Methods Forty-nine patients were selected for cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and were stratified according to the PSDSS retrospectively. Results Of 52 cytoreductive surgeries performed in 49 patients, HIPEC was performed in 33 cases (63%). We analyzed 31 cases of appendiceal and colorectal cancer patients who underwent CRS and HIPEC and 12 who underwent CRS only. 68% of the patients in whom CRS and HIPEC was performed were classified as PSDSS stage I or II. Contrastingly, all patients in whom CRS and HIPEC was unachievable were scored as PSDSS stage III or IV. Conclusions The outcomes of this study suggest that the PSDSS can be used as a preoperative assessment tool to predict disease resectability in the treatment of peritoneal surface malignancies.

Original languageEnglish (US)
Pages (from-to)403-407
Number of pages5
JournalAmerican Journal of Surgery
Volume207
Issue number3
DOIs
StatePublished - Mar 2014
Externally publishedYes

Keywords

  • Complete cytoreduction
  • Cytoreductive surgery
  • Hyperthermic intraperitoneal chemotherapy (HIPEC)
  • Peritoneal surface disease severity score (PSDSS)
  • Peritoneal surface malignancies

ASJC Scopus subject areas

  • Surgery

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