Abstract
Background We evaluated the clinical utility of the Peritoneal Surface Disease Severity Score (PSDSS) as a preoperative predictor of resectability in the treatment of peritoneal surface malignancies. Methods Forty-nine patients were selected for cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and were stratified according to the PSDSS retrospectively. Results Of 52 cytoreductive surgeries performed in 49 patients, HIPEC was performed in 33 cases (63%). We analyzed 31 cases of appendiceal and colorectal cancer patients who underwent CRS and HIPEC and 12 who underwent CRS only. 68% of the patients in whom CRS and HIPEC was performed were classified as PSDSS stage I or II. Contrastingly, all patients in whom CRS and HIPEC was unachievable were scored as PSDSS stage III or IV. Conclusions The outcomes of this study suggest that the PSDSS can be used as a preoperative assessment tool to predict disease resectability in the treatment of peritoneal surface malignancies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 403-407 |
| Number of pages | 5 |
| Journal | American Journal of Surgery |
| Volume | 207 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2014 |
| Externally published | Yes |
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Keywords
- Complete cytoreduction
- Cytoreductive surgery
- Hyperthermic intraperitoneal chemotherapy (HIPEC)
- Peritoneal surface disease severity score (PSDSS)
- Peritoneal surface malignancies
ASJC Scopus subject areas
- Surgery
Cite this
Peritoneal Surface Disease Severity Score as a predictor of resectability in the treatment of peritoneal surface malignancies. / Yoon, William; Alame, Amer; Berri, Richard.
In: American Journal of Surgery, Vol. 207, No. 3, 03.2014, p. 403-407.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Peritoneal Surface Disease Severity Score as a predictor of resectability in the treatment of peritoneal surface malignancies
AU - Yoon, William
AU - Alame, Amer
AU - Berri, Richard
PY - 2014/3
Y1 - 2014/3
N2 - Background We evaluated the clinical utility of the Peritoneal Surface Disease Severity Score (PSDSS) as a preoperative predictor of resectability in the treatment of peritoneal surface malignancies. Methods Forty-nine patients were selected for cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and were stratified according to the PSDSS retrospectively. Results Of 52 cytoreductive surgeries performed in 49 patients, HIPEC was performed in 33 cases (63%). We analyzed 31 cases of appendiceal and colorectal cancer patients who underwent CRS and HIPEC and 12 who underwent CRS only. 68% of the patients in whom CRS and HIPEC was performed were classified as PSDSS stage I or II. Contrastingly, all patients in whom CRS and HIPEC was unachievable were scored as PSDSS stage III or IV. Conclusions The outcomes of this study suggest that the PSDSS can be used as a preoperative assessment tool to predict disease resectability in the treatment of peritoneal surface malignancies.
AB - Background We evaluated the clinical utility of the Peritoneal Surface Disease Severity Score (PSDSS) as a preoperative predictor of resectability in the treatment of peritoneal surface malignancies. Methods Forty-nine patients were selected for cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and were stratified according to the PSDSS retrospectively. Results Of 52 cytoreductive surgeries performed in 49 patients, HIPEC was performed in 33 cases (63%). We analyzed 31 cases of appendiceal and colorectal cancer patients who underwent CRS and HIPEC and 12 who underwent CRS only. 68% of the patients in whom CRS and HIPEC was performed were classified as PSDSS stage I or II. Contrastingly, all patients in whom CRS and HIPEC was unachievable were scored as PSDSS stage III or IV. Conclusions The outcomes of this study suggest that the PSDSS can be used as a preoperative assessment tool to predict disease resectability in the treatment of peritoneal surface malignancies.
KW - Complete cytoreduction
KW - Cytoreductive surgery
KW - Hyperthermic intraperitoneal chemotherapy (HIPEC)
KW - Peritoneal surface disease severity score (PSDSS)
KW - Peritoneal surface malignancies
UR - http://www.scopus.com/inward/record.url?scp=84895497534&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84895497534&partnerID=8YFLogxK
U2 - 10.1016/j.amjsurg.2013.09.021
DO - 10.1016/j.amjsurg.2013.09.021
M3 - Article
C2 - 24444858
AN - SCOPUS:84895497534
VL - 207
SP - 403
EP - 407
JO - American Journal of Surgery
JF - American Journal of Surgery
SN - 0002-9610
IS - 3
ER -