Peripheral nonulcerative keratitis as a presenting sign of microscopic polyangiitis

Jason K. Darlington, Mark J Mannis, William A. Segal, Vahid Feiz, Donald E. Klug

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Purpose. To report a 16-year-old woman who had peripheral keratitis as a presenting sign of microscopic polyangiitis (MPA), which rapidly progressed to acute renal failure. Method. Case report. Results. The patient's vasculitis was diagnosed by renal biopsy, which was evaluated with histologic, immunofluorescence, and electron microscopy. The diagnosis was confirmed by laboratory study, which showed a positive antimyeloperoxidase antibody. Conclusion. MPA may rarely present with ocular findings and should be considered in the differential diagnosis when a patient has peripheral keratitis.

Original languageEnglish (US)
Pages (from-to)522-524
Number of pages3
JournalCornea
Volume20
Issue number5
DOIs
StatePublished - 2001

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Keywords

  • Antimyeloperoxidase antibody
  • Antineutrophil cytoplasmic antibody
  • Microscopic polyangiitis
  • Necrotizing glomerulonephritis
  • Peripheral nonulcerative keratitis
  • Peripheral ulcerative keratitis
  • Systemic vasculitis

ASJC Scopus subject areas

  • Ophthalmology

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