Peripheral competition in the control of sensory neuron numbers in Xenopus frogs reared with a single bilaterally innervated hindlimb

Alan H. Lamb, Michael J Ferns, Kari Klose

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Sensory neurons were counted in the hind-limb innervating spinal ganglia on both sides of juvenile Xenopus frogs which, as tadpoles, had had one hind limb bud amputated prior to innervation, and a channel made to allow innervation of the remaining limb bud from both sides. The total number of sensory neurons surviving on the two sides approximated the number on one side of normal frogs, the ipsilateral and contralateral numbers being negatively correlated. These effects differ markedly from the effects on motoneuron numbers, suggesting different control mechanisms of cell death in the two neuronal classes.

Original languageEnglish (US)
Pages (from-to)149-153
Number of pages5
JournalDevelopmental Brain Research
Volume45
Issue number1
DOIs
StatePublished - Jan 1 1989
Externally publishedYes

Fingerprint

Limb Buds
Sensory Receptor Cells
Hindlimb
Xenopus
Anura
Spinal Ganglia
Motor Neurons
Larva
Cell Death
Extremities

Keywords

  • Development
  • Neuronal death
  • Peripheral competition
  • Spinal ganglion
  • Xenopus

ASJC Scopus subject areas

  • Developmental Biology
  • Developmental Neuroscience

Cite this

Peripheral competition in the control of sensory neuron numbers in Xenopus frogs reared with a single bilaterally innervated hindlimb. / Lamb, Alan H.; Ferns, Michael J; Klose, Kari.

In: Developmental Brain Research, Vol. 45, No. 1, 01.01.1989, p. 149-153.

Research output: Contribution to journalArticle

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