Abstract
Sensory neurons were counted in the hind-limb innervating spinal ganglia on both sides of juvenile Xenopus frogs which, as tadpoles, had had one hind limb bud amputated prior to innervation, and a channel made to allow innervation of the remaining limb bud from both sides. The total number of sensory neurons surviving on the two sides approximated the number on one side of normal frogs, the ipsilateral and contralateral numbers being negatively correlated. These effects differ markedly from the effects on motoneuron numbers, suggesting different control mechanisms of cell death in the two neuronal classes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 149-153 |
| Number of pages | 5 |
| Journal | Developmental Brain Research |
| Volume | 45 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1989 |
| Externally published | Yes |
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Keywords
- Development
- Neuronal death
- Peripheral competition
- Spinal ganglion
- Xenopus
ASJC Scopus subject areas
- Developmental Biology
- Developmental Neuroscience
Cite this
Peripheral competition in the control of sensory neuron numbers in Xenopus frogs reared with a single bilaterally innervated hindlimb. / Lamb, Alan H.; Ferns, Michael J; Klose, Kari.
In: Developmental Brain Research, Vol. 45, No. 1, 01.01.1989, p. 149-153.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Peripheral competition in the control of sensory neuron numbers in Xenopus frogs reared with a single bilaterally innervated hindlimb
AU - Lamb, Alan H.
AU - Ferns, Michael J
AU - Klose, Kari
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Sensory neurons were counted in the hind-limb innervating spinal ganglia on both sides of juvenile Xenopus frogs which, as tadpoles, had had one hind limb bud amputated prior to innervation, and a channel made to allow innervation of the remaining limb bud from both sides. The total number of sensory neurons surviving on the two sides approximated the number on one side of normal frogs, the ipsilateral and contralateral numbers being negatively correlated. These effects differ markedly from the effects on motoneuron numbers, suggesting different control mechanisms of cell death in the two neuronal classes.
AB - Sensory neurons were counted in the hind-limb innervating spinal ganglia on both sides of juvenile Xenopus frogs which, as tadpoles, had had one hind limb bud amputated prior to innervation, and a channel made to allow innervation of the remaining limb bud from both sides. The total number of sensory neurons surviving on the two sides approximated the number on one side of normal frogs, the ipsilateral and contralateral numbers being negatively correlated. These effects differ markedly from the effects on motoneuron numbers, suggesting different control mechanisms of cell death in the two neuronal classes.
KW - Development
KW - Neuronal death
KW - Peripheral competition
KW - Spinal ganglion
KW - Xenopus
UR - http://www.scopus.com/inward/record.url?scp=0024581397&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024581397&partnerID=8YFLogxK
U2 - 10.1016/0165-3806(89)90016-3
DO - 10.1016/0165-3806(89)90016-3
M3 - Article
C2 - 2917408
AN - SCOPUS:0024581397
VL - 45
SP - 149
EP - 153
JO - Developmental Brain Research
JF - Developmental Brain Research
SN - 0165-3806
IS - 1
ER -