Peripheral artery disease and genetics

Is there a cause-and-effect relationship?

Yung-wei Chi, Michael R. Jaff

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Peripheral artery disease (PAD) is a major health problem worldwide, affecting millions of patients. Although cardiovascular risk factors, such as diabetes, tobacco use, hypertension, and hypercholesterolemia have been associated with the development of PAD, the possible existence of an inherited genetic predisposition to PAD has been investigated in numerous familial aggregation studies. A link between genetics and PAD may open new avenues for the prevention of this morbid and mortal disorder. This is an overview of the potential association between genetics and PAD.

Original languageEnglish (US)
Pages (from-to)170-176
Number of pages7
JournalPostgraduate Medicine
Volume122
Issue number4
DOIs
StatePublished - Jul 2010
Externally publishedYes

Fingerprint

Peripheral Arterial Disease
Tobacco Use
Genetic Predisposition to Disease
Hypercholesterolemia
Hypertension

Keywords

  • Ankle-brachial index
  • Genetic associations
  • Peripheral artery disease

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Peripheral artery disease and genetics : Is there a cause-and-effect relationship? / Chi, Yung-wei; Jaff, Michael R.

In: Postgraduate Medicine, Vol. 122, No. 4, 07.2010, p. 170-176.

Research output: Contribution to journalArticle

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