Periodontal disease, periodontal treatment and systemic nitric oxide in dogs

A. Nemec, Frank J Verstraete, A. Jerin, M. Šentjurc, Philip H Kass, M. Petelin, Z. Pavlica

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Thirty-two client-owned dogs treated for periodontal disease were divided in group 1 if no periodontitis, group 2 if ≤25%, and group 3 if >25% of the teeth present were affected with periodontitis. Blood was tested before and 2. weeks after periodontal therapy for nitrosyl hemoglobin (HbNO), plasma nitrite/nitrate (NOx) and 3-nitrotyrosine (NT) levels. No HbNO was detected in any of the animals tested. There was no significant difference in the NOx plasma levels within each group or across the groups before and after the treatment, but a noticeable increase in NOx plasma levels was observed in group 3 after the treatment. Plasma NT was detected in only one third of the animals. NO levels varied greatly across individual dogs. The data are suggestive of an overall increase in systemic NO response 2. weeks after periodontal treatment in dogs with advanced periodontal disease, but the response is greatly individually-dependent.

Original languageEnglish (US)
Pages (from-to)542-544
Number of pages3
JournalResearch in Veterinary Science
Volume94
Issue number3
DOIs
StatePublished - Jun 2013

Fingerprint

Periodontal Diseases
nitric oxide
Nitric Oxide
Dogs
dogs
Periodontitis
nitrites
hemoglobin
animals
teeth
Nitrites
nitrates
Nitrates
therapeutics
Tooth
blood
periodontal diseases
periodontitis
3-nitrotyrosine
glycosylated-nitric oxide complex hemoglobin A

Keywords

  • Dogs
  • Nitric oxide
  • Periodontal disease
  • Periodontal treatment
  • Periodontitis
  • Systemic host response

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Periodontal disease, periodontal treatment and systemic nitric oxide in dogs. / Nemec, A.; Verstraete, Frank J; Jerin, A.; Šentjurc, M.; Kass, Philip H; Petelin, M.; Pavlica, Z.

In: Research in Veterinary Science, Vol. 94, No. 3, 06.2013, p. 542-544.

Research output: Contribution to journalArticle

Nemec, A. ; Verstraete, Frank J ; Jerin, A. ; Šentjurc, M. ; Kass, Philip H ; Petelin, M. ; Pavlica, Z. / Periodontal disease, periodontal treatment and systemic nitric oxide in dogs. In: Research in Veterinary Science. 2013 ; Vol. 94, No. 3. pp. 542-544.
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