Performance of the Tachyon time-of-flight PET camera

Q. Peng, W. S. Choong, C. Vu, J. S. Huber, M. Janecek, D. Wilson, R. H. Huesman, Jinyi Qi, Jian Zhou, W. W. Moses

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We have constructed and characterized a time-of-flight Positron Emission Tomography (TOF PET) camera called the Tachyon. The Tachyon is a single-ring Lutetium Oxyorthosilicate (LSO) based camera designed to obtain significantly better timing resolution than the ~ 550 ps found in present commercial TOF cameras, in order to quantify the benefit of improved TOF resolution for clinically relevant tasks. The Tachyon's detector module is optimized for timing by coupling the 6.15 × 25 mm2 side of 6.15 × 6.15 × 25mm3 LSO scintillator crystals onto a 1-inch diameter Hamamatsu R-9800 PMT with a super-bialkali photocathode. We characterized the camera according to the NEMA NU 2-2012 standard, measuring the energy resolution, timing resolution, spatial resolution, noise equivalent count rates and sensitivity. The Tachyon achieved a coincidence timing resolution of 314 ps + / - 20 ps FWHM over all crystal-crystal combinations. Experiments were performed with the NEMA body phantom to assess the imaging performance improvement over non-TOF PET. The results show that at a matched contrast, incorporating 314 ps TOF reduces the standard deviation of the contrast by a factor of about 2.3.

Original languageEnglish (US)
Article number7018978
Pages (from-to)111-119
Number of pages9
JournalIEEE Transactions on Nuclear Science
Volume62
Issue number1
DOIs
StatePublished - Feb 6 2015

Keywords

  • Signal-to-noise ratio
  • time-of-flight
  • timing resolution

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Nuclear Energy and Engineering
  • Nuclear and High Energy Physics

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  • Cite this

    Peng, Q., Choong, W. S., Vu, C., Huber, J. S., Janecek, M., Wilson, D., Huesman, R. H., Qi, J., Zhou, J., & Moses, W. W. (2015). Performance of the Tachyon time-of-flight PET camera. IEEE Transactions on Nuclear Science, 62(1), 111-119. [7018978]. https://doi.org/10.1109/TNS.2014.2375176