Percutaneous ultrasound-guided radiofrequency heat ablation for treatment of hyperthyroidism in cats

Kevin F. Mallery, Rachel E Pollard, Richard W Nelson, William J. Hornof, Edward C Feldman

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Objective-To determine efficacy and safety of percutaneous radiofrequency heat ablation for treatment of hyperthyroidism in cats. Design-Prospective study. Animals-9 cats. Procedure-Hyperthyroidism was diagnosed via clinical signs and high serum total (TT4) and free thyroxine (fT4) concentrations. One or 2 hyperfunctional cervical thyroid nodules were detected by use of scintigraphy and ultrasonography. If cats had 1 abnormal thyroid lobe, heat ablation was performed on that lobe; if cats had 2 abnormal lobes, heat ablation was applied to the larger lobe. Overall, heat ablation was performed 14 times in the 9 cats. Clinical signs and serum TT4, fT 4, and calcium concentrations were monitored daily for 2 days after the procedure, weekly for the first month, and then monthly. Laryngeal function was evaluated and cervical ultrasonography and thyroid scintigraphy were also performed. Monitoring continued for as long as 9 months after heat ablation if a cat became euthyroid or until an owner chose an alternative treatment because of recurrence of hyperthyroidism. Results-Serum TT4 and fT 4 concentrations transiently decreased after all 14 heat ablation procedures (≤ reference range after 10 of 14 treatments) within 2 days after the procedure. Cats were euthyroid for 0 to 18 months (mean, 4 months). Hyperthyroidism recurred in all cats. Adverse effects included transient Horner's syndrome (2 cats) and laryngeal paralysis without clinical signs (1 cat). Conclusions and Clinical Relevance-Percutaneous heat ablation as a treatment for hyperthyroidism in cats is effective transiently but not permanently.

Original languageEnglish (US)
Pages (from-to)1602-1607
Number of pages6
JournalJournal of the American Veterinary Medical Association
Volume223
Issue number11
DOIs
StatePublished - Dec 1 2003

ASJC Scopus subject areas

  • veterinary(all)

Fingerprint Dive into the research topics of 'Percutaneous ultrasound-guided radiofrequency heat ablation for treatment of hyperthyroidism in cats'. Together they form a unique fingerprint.

  • Cite this