Percutaneous ultrasonographically guided radiofrequency heat ablation for treatment of primary hyperparathyroidism in dogs

Rachel E Pollard, Craig D. Long, Richard W Nelson, William J. Hornof, Edward C Feldman

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

Objective - To evaluate the efficacy and safety of ultrasonographically guided radiofrequency heat ablation of parathyroid masses in dogs with primary hyperparathyroidism. Design - Clinical trial. Animals - 11 dogs. Procedure - In all dogs, either 1 or 2 parathyroid masses were evident ultrasonographically. Dogs were anesthetized, and a 20-gauge over-the-needle catheter was directed into the parathyroid mass via ultrasonographic guidance. Radiofrequency heat was applied to the stylet of the catheter until there was sonographically apparent change to the entire parenchyma of the mass. Serum total and ionized calcium and parathyroid hormone concentrations were monitored daily for 5 days after the ablation procedure and again at 1, 2, and 3-month intervals, if possible. Dogs were monitored for adverse effects. Results - One treatment was required in 6 dogs, 2 treatments were required in 2 dogs, and treatment was unsuccessful in 3 dogs. Serum total and ionized calcium concentrations were within reference ranges within 2 days of the last procedure in all 8 successfully treated dogs. Serum parathyroid hormone concentration was decreased 24 hours after treatment in all 8 dogs. Hypocalcemia developed in 5 of the 8 successfully treated dogs, all of which required treatment. One dog had a transient voice change. Other adverse effects were not reported. Conclusions and Clinical Relevance - Ultrasonographically guided radiofrequency heat ablation of parathyroid masses is a safe and effective alternative to surgery in doqs with primary hyperparathyroidism.

Original languageEnglish (US)
Pages (from-to)1106-1110
Number of pages5
JournalJournal of the American Veterinary Medical Association
Volume218
Issue number7
StatePublished - Apr 1 2001

ASJC Scopus subject areas

  • veterinary(all)

Fingerprint Dive into the research topics of 'Percutaneous ultrasonographically guided radiofrequency heat ablation for treatment of primary hyperparathyroidism in dogs'. Together they form a unique fingerprint.

Cite this