Abstract
Ultrasound-guided percutaneous ethanol injection (PEI) was evaluated in 4 cats as a treatment for a unilateral hyperplastic thyroid nodule. Cats were anesthetized with a short-acting agent, and a 27-gauge needle was directed into the thyroid nodule with guidance by ultrasound. A precalculated dose of 96% ethanol solution was injected, and diffusion of the fluid throughout the gland was readily apparent. Serum thyroxine (T4) and free T4 concentrations decreased to or below reference ranges in all cats within 48 hours, and remained so during the 12-month study period. All cats have been assessed as clinically normal and have had no clinical signs of hyperthyroidism since PEI. No severe adverse effects were observed. Results of follow-up pertechnetate scans were normal in 2 cats and abnormal in 2 cats. We concluded that PEI is likely a safe and efficacious treatment for hyperthyroidism caused by a unilateral hyperplastic nodule in cats.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1298-1302+1270 |
| Journal | Journal of the American Veterinary Medical Association |
| Volume | 218 |
| Issue number | 8 |
| State | Published - Apr 15 2001 |
| Externally published | Yes |
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ASJC Scopus subject areas
- veterinary(all)
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Percutaneous ethanol injection for treatment of unilateral hyperplastic thyroid nodules in cats. / Goldstein, R. E.; Long, C.; Swift, N. C.; Hornof, W. J.; Nelson, Richard W; Nyland, T. G.; Feldman, Edward C.
In: Journal of the American Veterinary Medical Association, Vol. 218, No. 8, 15.04.2001, p. 1298-1302+1270.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Percutaneous ethanol injection for treatment of unilateral hyperplastic thyroid nodules in cats
AU - Goldstein, R. E.
AU - Long, C.
AU - Swift, N. C.
AU - Hornof, W. J.
AU - Nelson, Richard W
AU - Nyland, T. G.
AU - Feldman, Edward C
PY - 2001/4/15
Y1 - 2001/4/15
N2 - Ultrasound-guided percutaneous ethanol injection (PEI) was evaluated in 4 cats as a treatment for a unilateral hyperplastic thyroid nodule. Cats were anesthetized with a short-acting agent, and a 27-gauge needle was directed into the thyroid nodule with guidance by ultrasound. A precalculated dose of 96% ethanol solution was injected, and diffusion of the fluid throughout the gland was readily apparent. Serum thyroxine (T4) and free T4 concentrations decreased to or below reference ranges in all cats within 48 hours, and remained so during the 12-month study period. All cats have been assessed as clinically normal and have had no clinical signs of hyperthyroidism since PEI. No severe adverse effects were observed. Results of follow-up pertechnetate scans were normal in 2 cats and abnormal in 2 cats. We concluded that PEI is likely a safe and efficacious treatment for hyperthyroidism caused by a unilateral hyperplastic nodule in cats.
AB - Ultrasound-guided percutaneous ethanol injection (PEI) was evaluated in 4 cats as a treatment for a unilateral hyperplastic thyroid nodule. Cats were anesthetized with a short-acting agent, and a 27-gauge needle was directed into the thyroid nodule with guidance by ultrasound. A precalculated dose of 96% ethanol solution was injected, and diffusion of the fluid throughout the gland was readily apparent. Serum thyroxine (T4) and free T4 concentrations decreased to or below reference ranges in all cats within 48 hours, and remained so during the 12-month study period. All cats have been assessed as clinically normal and have had no clinical signs of hyperthyroidism since PEI. No severe adverse effects were observed. Results of follow-up pertechnetate scans were normal in 2 cats and abnormal in 2 cats. We concluded that PEI is likely a safe and efficacious treatment for hyperthyroidism caused by a unilateral hyperplastic nodule in cats.
UR - http://www.scopus.com/inward/record.url?scp=0035871348&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035871348&partnerID=8YFLogxK
M3 - Article
C2 - 11330617
AN - SCOPUS:0035871348
VL - 218
SP - 1298-1302+1270
JO - Journal of the American Veterinary Medical Association
JF - Journal of the American Veterinary Medical Association
SN - 0003-1488
IS - 8
ER -