Perceptual and attentional asymmetries in schizophrenia: Further evidence for a left hemisphere deficit

Cameron S Carter, Lynn C. Robertson, Thomas E Nordahl, Marc Chaderjian, Linda Oshora-Celaya

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

Increasing evidence suggests the presence of a lateralizing attentional deficit in schizophrenia. In the present study, 23 unmedicated patients with schizophrenia (mean age = 32.1 years) and 14 age- and sex-matched normal subjects were studied with the Global/Local Task to provide converging evidence for the presence of a left-hemisphere-associated attentional deficit in schizophrenia. This task is sensitive to the integrity of mechanisms involved in discriminating local and global elements of stimuli. Previous research has linked the discrimination of local targets to left hemispheric processes and the discrimination of global targets to right hemispheric processes. As predicted, patients were impaired in the detection of local level targets, consistent with a left hemispheric deficit. The degree of impairment correlated with the patient's level of auditory hallucinations. These results are consistent with previous studies showing an asymmetrical attentional deficit in schizophrenia and left hemispheric dysfunction. The correlation between this deficit and auditory hallucinations is consistent with a hypothesized relationship between this symptom in schizophrenia and left temporal pathology.

Original languageEnglish (US)
Pages (from-to)111-119
Number of pages9
JournalPsychiatry Research
Volume62
Issue number2
DOIs
StatePublished - May 17 1996
Externally publishedYes

    Fingerprint

Keywords

  • Attention
  • Hallucinations auditory
  • Laterality
  • Left hemisphere
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

Cite this