TY - JOUR
T1 - Pemphigus foliaceus in the horse
T2 - A retrospective study of 20 cases
AU - Vandenabeele, Sophie I J
AU - White, Stephen D
AU - Affolter, Verena K
AU - Kass, Philip H
AU - Ihrke, Peter J.
PY - 2004/12
Y1 - 2004/12
N2 - Twenty horses with pemphigus foliaceus were seen over a period of 15 years in a veterinary medical teaching hospital. Breeds seen were seven quarterhorses, five thoroughbreds, three cross-bred horses, two Arabians and one of each of the following: standardbred, Tennessee walker and warmblood. There was no breed, age or sex predisposition. Nine were mares, ten were geldings and one was a stallion. Ages ranged from 2.5 months to 25 years, with a mean of 8.6 years. Sixteen (80%) of the pemphigus foliaceus horses first exhibited signs between September and February. There was a statistically significant more common occurrence of pemphigus foliaceus during those months. Signs in the four other horses were first noted in March, May or June. Three of those horses were < 13 months of age. Oedema (14/20) and crusts (13/20) were the most common lesions. Pain was present in 9/20 horses, pruritus in 7/20 and pyrexia in 7/20. Follow-up was available for 13 horses. Five of these horses were euthanased. In three horses the reason for euthanasia was laminitis secondary to treatment. Four horses remained lesion-free after medication was discontinued. Two horses required maintenance medication and are doing well at the time of writing.
AB - Twenty horses with pemphigus foliaceus were seen over a period of 15 years in a veterinary medical teaching hospital. Breeds seen were seven quarterhorses, five thoroughbreds, three cross-bred horses, two Arabians and one of each of the following: standardbred, Tennessee walker and warmblood. There was no breed, age or sex predisposition. Nine were mares, ten were geldings and one was a stallion. Ages ranged from 2.5 months to 25 years, with a mean of 8.6 years. Sixteen (80%) of the pemphigus foliaceus horses first exhibited signs between September and February. There was a statistically significant more common occurrence of pemphigus foliaceus during those months. Signs in the four other horses were first noted in March, May or June. Three of those horses were < 13 months of age. Oedema (14/20) and crusts (13/20) were the most common lesions. Pain was present in 9/20 horses, pruritus in 7/20 and pyrexia in 7/20. Follow-up was available for 13 horses. Five of these horses were euthanased. In three horses the reason for euthanasia was laminitis secondary to treatment. Four horses remained lesion-free after medication was discontinued. Two horses required maintenance medication and are doing well at the time of writing.
KW - Dexamethasone
KW - Equine pemphigus foliaceus
KW - Horse
KW - Laminitis
KW - Seasonality
KW - September to February
UR - http://www.scopus.com/inward/record.url?scp=11244295039&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=11244295039&partnerID=8YFLogxK
U2 - 10.1111/j.1365-3164.2004.00423.x
DO - 10.1111/j.1365-3164.2004.00423.x
M3 - Article
C2 - 15585014
AN - SCOPUS:11244295039
VL - 15
SP - 381
EP - 388
JO - Veterinary Dermatology
JF - Veterinary Dermatology
SN - 0959-4493
IS - 6
ER -