Pelvic lymphadenectomy in prostate cancer

B. N. Breyer, K. L. Greene, Marc Dall'Era, B. J. Davies, C. J. Kane

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

This review analyzes the anatomy of the prostate gland's lymphatic drainage, the optimal anatomic extend of pelvic lymph node dissection (PLND) and which dissection may be superior, who should undergo a PLND during prostatectomy, and its potential therapeutic benefits and complications. The prostate gland's lymphatic drainage can be variable, but frequently metastatic disease is found in the internal iliac chain. We conclude that the extended PLND yields the most lymph nodes and therefore may be superior. Some have demonstrated an unproven survival benefit after performing an extended PLND, possibly from removal of occult disease or from more accurate staging.

Original languageEnglish (US)
Pages (from-to)320-324
Number of pages5
JournalProstate Cancer and Prostatic Diseases
Volume11
Issue number4
DOIs
StatePublished - 2008

ASJC Scopus subject areas

  • Oncology
  • Urology
  • Cancer Research

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    Breyer, B. N., Greene, K. L., Dall'Era, M., Davies, B. J., & Kane, C. J. (2008). Pelvic lymphadenectomy in prostate cancer. Prostate Cancer and Prostatic Diseases, 11(4), 320-324. https://doi.org/10.1038/pcan.2008.29