Pediatric en bloc kidney transplantation into pediatric recipients

Keith K. Lau, Gerre M. Berg, Yolanda G. Schjoneman, Richard V Perez, Lavjay Butani

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

As a result of the ongoing shortage in organ supply, en bloc renal transplantation from small donors has become more common for adult recipients with ESRD. However, because of concern for higher complication rates and sub-optimal outcomes, it is not being performed in every center, and data describing its use in pediatric recipients are even more limited. We retrospectively studied three patients who have undergone en bloc renal transplantation at our center. Median age at transplantation was 16.7 yr with a median follow-up of 1.2 yr. Donor age ranged from nine to 49 months with weight ranging from 10 to 22 kg. There were no post-operative thrombotic complications. All grafts showed increased renal size at follow-up by ultrasound. There was no clinical or histological rejection at last follow-up. To the best of our knowledge, this is the first report on the outcomes of en bloc kidney transplantation from pediatric donors into pediatric recipients. Based on our experience, albeit very limited, we feel that en bloc renal transplantation from young donors is an acceptable and safe procedure with low complication rates in pediatric recipients and should be given consideration to minimize wait times on the wait list and to improve quality of life.

Original languageEnglish (US)
Pages (from-to)100-104
Number of pages5
JournalPediatric Transplantation
Volume14
Issue number1
DOIs
StatePublished - Feb 2010

Fingerprint

Kidney Transplantation
Tissue Donors
Pediatrics
Chronic Kidney Failure
Transplantation
Quality of Life
Transplants
Kidney
Weights and Measures

Keywords

  • En block
  • Kidney transplantation
  • Pediatrics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

Cite this

Pediatric en bloc kidney transplantation into pediatric recipients. / Lau, Keith K.; Berg, Gerre M.; Schjoneman, Yolanda G.; Perez, Richard V; Butani, Lavjay.

In: Pediatric Transplantation, Vol. 14, No. 1, 02.2010, p. 100-104.

Research output: Contribution to journalArticle

Lau, Keith K. ; Berg, Gerre M. ; Schjoneman, Yolanda G. ; Perez, Richard V ; Butani, Lavjay. / Pediatric en bloc kidney transplantation into pediatric recipients. In: Pediatric Transplantation. 2010 ; Vol. 14, No. 1. pp. 100-104.
@article{0c3d17ea2c1d45e39a42667346fa658f,
title = "Pediatric en bloc kidney transplantation into pediatric recipients",
abstract = "As a result of the ongoing shortage in organ supply, en bloc renal transplantation from small donors has become more common for adult recipients with ESRD. However, because of concern for higher complication rates and sub-optimal outcomes, it is not being performed in every center, and data describing its use in pediatric recipients are even more limited. We retrospectively studied three patients who have undergone en bloc renal transplantation at our center. Median age at transplantation was 16.7 yr with a median follow-up of 1.2 yr. Donor age ranged from nine to 49 months with weight ranging from 10 to 22 kg. There were no post-operative thrombotic complications. All grafts showed increased renal size at follow-up by ultrasound. There was no clinical or histological rejection at last follow-up. To the best of our knowledge, this is the first report on the outcomes of en bloc kidney transplantation from pediatric donors into pediatric recipients. Based on our experience, albeit very limited, we feel that en bloc renal transplantation from young donors is an acceptable and safe procedure with low complication rates in pediatric recipients and should be given consideration to minimize wait times on the wait list and to improve quality of life.",
keywords = "En block, Kidney transplantation, Pediatrics",
author = "Lau, {Keith K.} and Berg, {Gerre M.} and Schjoneman, {Yolanda G.} and Perez, {Richard V} and Lavjay Butani",
year = "2010",
month = "2",
doi = "10.1111/j.1399-3046.2009.01137.x",
language = "English (US)",
volume = "14",
pages = "100--104",
journal = "Pediatric Transplantation",
issn = "1397-3142",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Pediatric en bloc kidney transplantation into pediatric recipients

AU - Lau, Keith K.

AU - Berg, Gerre M.

AU - Schjoneman, Yolanda G.

AU - Perez, Richard V

AU - Butani, Lavjay

PY - 2010/2

Y1 - 2010/2

N2 - As a result of the ongoing shortage in organ supply, en bloc renal transplantation from small donors has become more common for adult recipients with ESRD. However, because of concern for higher complication rates and sub-optimal outcomes, it is not being performed in every center, and data describing its use in pediatric recipients are even more limited. We retrospectively studied three patients who have undergone en bloc renal transplantation at our center. Median age at transplantation was 16.7 yr with a median follow-up of 1.2 yr. Donor age ranged from nine to 49 months with weight ranging from 10 to 22 kg. There were no post-operative thrombotic complications. All grafts showed increased renal size at follow-up by ultrasound. There was no clinical or histological rejection at last follow-up. To the best of our knowledge, this is the first report on the outcomes of en bloc kidney transplantation from pediatric donors into pediatric recipients. Based on our experience, albeit very limited, we feel that en bloc renal transplantation from young donors is an acceptable and safe procedure with low complication rates in pediatric recipients and should be given consideration to minimize wait times on the wait list and to improve quality of life.

AB - As a result of the ongoing shortage in organ supply, en bloc renal transplantation from small donors has become more common for adult recipients with ESRD. However, because of concern for higher complication rates and sub-optimal outcomes, it is not being performed in every center, and data describing its use in pediatric recipients are even more limited. We retrospectively studied three patients who have undergone en bloc renal transplantation at our center. Median age at transplantation was 16.7 yr with a median follow-up of 1.2 yr. Donor age ranged from nine to 49 months with weight ranging from 10 to 22 kg. There were no post-operative thrombotic complications. All grafts showed increased renal size at follow-up by ultrasound. There was no clinical or histological rejection at last follow-up. To the best of our knowledge, this is the first report on the outcomes of en bloc kidney transplantation from pediatric donors into pediatric recipients. Based on our experience, albeit very limited, we feel that en bloc renal transplantation from young donors is an acceptable and safe procedure with low complication rates in pediatric recipients and should be given consideration to minimize wait times on the wait list and to improve quality of life.

KW - En block

KW - Kidney transplantation

KW - Pediatrics

UR - http://www.scopus.com/inward/record.url?scp=74349108553&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74349108553&partnerID=8YFLogxK

U2 - 10.1111/j.1399-3046.2009.01137.x

DO - 10.1111/j.1399-3046.2009.01137.x

M3 - Article

C2 - 19490484

AN - SCOPUS:74349108553

VL - 14

SP - 100

EP - 104

JO - Pediatric Transplantation

JF - Pediatric Transplantation

SN - 1397-3142

IS - 1

ER -