Abstract
Extracorporeal life support (ECLS) for pediatric burn patients is a viable option for respiratory failure that is unresponsive to maximal conventional therapy. No criteria have been identified that are predictive of the success of the use of ECLS for these patients. This article presents a retrospective review of the pediatric burn patients placed on ECLS at a single pediatric medical center. It was found that 12 patients (mean age, 30.3 months; range 6 to 69 months) were placed on ECLS because of profound pulmonary failure that was unresponsive to aggressive ventilatory support. The mean size of the burns of these patients was 50.2% of the total body surface area (average size of full-thickness burns, 41.8% total body surface area), with 6 patients having scald burns and 6 having flame burns. The overall survival was 67% (8 of 12). Nonsurvivors had greater positive end- expiratory pressure, mean airway pressure, peak inspiratory pressure, and oxygenation index before ECLS. It is felt that ECLS is a life-saying therapy for pediatric patients with thermal injury. Greater ventilator requirements before ECLS are associated with nonsurvival. Early institution of ECLS in pediatric burn patients with Severe respiratory failure may prevent excessive barotrauma and thus discourage the onset of irreversible lung injury.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 145-150 |
| Number of pages | 6 |
| Journal | Journal of Burn Care and Rehabilitation |
| Volume | 20 |
| Issue number | 2 |
| State | Published - Mar 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Rehabilitation
- Surgery
- Nursing(all)
- Health Professions(all)
- Emergency Medicine
Cite this
Pediatric burn patients with respiratory failure : Predictors of outcome with the use of extracorporeal life support. / Kane, Timothy D.; Greenhalgh, David G; Warden, Glenn D.; Goretsky, Michael J.; Ryckman, Frederick C.; Warner, Brad W.
In: Journal of Burn Care and Rehabilitation, Vol. 20, No. 2, 03.1999, p. 145-150.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pediatric burn patients with respiratory failure
T2 - Predictors of outcome with the use of extracorporeal life support
AU - Kane, Timothy D.
AU - Greenhalgh, David G
AU - Warden, Glenn D.
AU - Goretsky, Michael J.
AU - Ryckman, Frederick C.
AU - Warner, Brad W.
PY - 1999/3
Y1 - 1999/3
N2 - Extracorporeal life support (ECLS) for pediatric burn patients is a viable option for respiratory failure that is unresponsive to maximal conventional therapy. No criteria have been identified that are predictive of the success of the use of ECLS for these patients. This article presents a retrospective review of the pediatric burn patients placed on ECLS at a single pediatric medical center. It was found that 12 patients (mean age, 30.3 months; range 6 to 69 months) were placed on ECLS because of profound pulmonary failure that was unresponsive to aggressive ventilatory support. The mean size of the burns of these patients was 50.2% of the total body surface area (average size of full-thickness burns, 41.8% total body surface area), with 6 patients having scald burns and 6 having flame burns. The overall survival was 67% (8 of 12). Nonsurvivors had greater positive end- expiratory pressure, mean airway pressure, peak inspiratory pressure, and oxygenation index before ECLS. It is felt that ECLS is a life-saying therapy for pediatric patients with thermal injury. Greater ventilator requirements before ECLS are associated with nonsurvival. Early institution of ECLS in pediatric burn patients with Severe respiratory failure may prevent excessive barotrauma and thus discourage the onset of irreversible lung injury.
AB - Extracorporeal life support (ECLS) for pediatric burn patients is a viable option for respiratory failure that is unresponsive to maximal conventional therapy. No criteria have been identified that are predictive of the success of the use of ECLS for these patients. This article presents a retrospective review of the pediatric burn patients placed on ECLS at a single pediatric medical center. It was found that 12 patients (mean age, 30.3 months; range 6 to 69 months) were placed on ECLS because of profound pulmonary failure that was unresponsive to aggressive ventilatory support. The mean size of the burns of these patients was 50.2% of the total body surface area (average size of full-thickness burns, 41.8% total body surface area), with 6 patients having scald burns and 6 having flame burns. The overall survival was 67% (8 of 12). Nonsurvivors had greater positive end- expiratory pressure, mean airway pressure, peak inspiratory pressure, and oxygenation index before ECLS. It is felt that ECLS is a life-saying therapy for pediatric patients with thermal injury. Greater ventilator requirements before ECLS are associated with nonsurvival. Early institution of ECLS in pediatric burn patients with Severe respiratory failure may prevent excessive barotrauma and thus discourage the onset of irreversible lung injury.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032993897&partnerID=8YFLogxK
M3 - Article
C2 - 10188112
AN - SCOPUS:0032993897
VL - 20
SP - 145
EP - 150
JO - Journal of Burn Care and Research
JF - Journal of Burn Care and Research
SN - 1559-047X
IS - 2
ER -