Pay close attention to severe adverse effects of tumor necrosis factor blockers

Qingtong Wang; Wei Wei

Pay close attention to severe adverse effects of tumor necrosis factor blockers

Qingtong Wang, Wei Wei

Research output: Contribution to journal › Article › peer-review

Abstract

Tumor necrosis factor (TNF) blockers are promising therapeutic agents for patients with conventional therapy insensitive inflammatory diseases. Unfortunately, their use has been associated with an increased rate of malignancies, leukemia, psoriasis and other immune diseases. The U. S. Food and Drug Administration (FDA) is requiring stronger warnings in the prescribing information for TNF blockers. Healthcare Professionals should pay close attention to severe adverse effects of TNF blockers and drug safety.

Original language	English (US)
Journal	Chinese Pharmacological Bulletin
Volume	25
Issue number	9
State	Published - Jan 1 2009
Externally published	Yes

Keywords

Adalimumab
Adverse effect
Etanercept
Infliximab
Rational administration
Tumor necrosis factor blocker

ASJC Scopus subject areas

Pharmacology

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abstract = "Tumor necrosis factor (TNF) blockers are promising therapeutic agents for patients with conventional therapy insensitive inflammatory diseases. Unfortunately, their use has been associated with an increased rate of malignancies, leukemia, psoriasis and other immune diseases. The U. S. Food and Drug Administration (FDA) is requiring stronger warnings in the prescribing information for TNF blockers. Healthcare Professionals should pay close attention to severe adverse effects of TNF blockers and drug safety.",

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AB - Tumor necrosis factor (TNF) blockers are promising therapeutic agents for patients with conventional therapy insensitive inflammatory diseases. Unfortunately, their use has been associated with an increased rate of malignancies, leukemia, psoriasis and other immune diseases. The U. S. Food and Drug Administration (FDA) is requiring stronger warnings in the prescribing information for TNF blockers. Healthcare Professionals should pay close attention to severe adverse effects of TNF blockers and drug safety.

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