Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion

Arnold Kriegstein; Stephen C Noctor; Veronica Martinez-Cerdeno

doi:10.1038/nrn2008

Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion

Arnold Kriegstein, Stephen C Noctor, Veronica Martinez-Cerdeno

Research output: Contribution to journal › Article › peer-review

472 Scopus citations

Abstract

The dramatic evolutionary expansion of the cerebral cortex of Homo sapiens underlies our unique higher cortical functions, and therefore bears on the ultimate issue of what makes us human. Recent insights into developmental events during early proliferative stages of cortical development indicate how neural stem and progenitor cells might interact to produce cortical expansion during development, and could shed light on evolutionary changes in cortical structure.

Original language	English (US)
Pages (from-to)	883-890
Number of pages	8
Journal	Nature Reviews Neuroscience
Volume	7
Issue number	11
DOIs	https://doi.org/10.1038/nrn2008
State	Published - Nov 2006

ASJC Scopus subject areas

Neuroscience(all)
Cell Biology

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10.1038/nrn2008

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abstract = "The dramatic evolutionary expansion of the cerebral cortex of Homo sapiens underlies our unique higher cortical functions, and therefore bears on the ultimate issue of what makes us human. Recent insights into developmental events during early proliferative stages of cortical development indicate how neural stem and progenitor cells might interact to produce cortical expansion during development, and could shed light on evolutionary changes in cortical structure.",

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