Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion

Research output: Contribution to journalArticle

452 Citations (Scopus)

Abstract

The dramatic evolutionary expansion of the cerebral cortex of Homo sapiens underlies our unique higher cortical functions, and therefore bears on the ultimate issue of what makes us human. Recent insights into developmental events during early proliferative stages of cortical development indicate how neural stem and progenitor cells might interact to produce cortical expansion during development, and could shed light on evolutionary changes in cortical structure.

Original languageEnglish (US)
Pages (from-to)883-890
Number of pages8
JournalNature Reviews Neuroscience
Volume7
Issue number11
DOIs
StatePublished - Nov 2006

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Neural Stem Cells
Cell Division
Stem Cells
Cerebral Cortex

ASJC Scopus subject areas

  • Neuroscience(all)
  • Cell Biology

Cite this

Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion. / Kriegstein, Arnold; Noctor, Stephen C; Martinez-Cerdeno, Veronica.

In: Nature Reviews Neuroscience, Vol. 7, No. 11, 11.2006, p. 883-890.

Research output: Contribution to journalArticle

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