Patient-specific knee joint finite element model validation with high-accuracy kinematics from biplane dynamic Roentgen stereogrammetric analysis

G. Papaioannou, G. Nianios, C. Mitrogiannis, David P Fyhrie, S. Tashman, K. H. Yang

Research output: Contribution to journalArticle

48 Scopus citations


Little is known about in vivo menisci loads and displacements in the knee during strenuous activities. A new method that combines high-speed kinematics measured with biplane dynamic Roentgen stereogrammetric analysis (DRSA) and a subject-specific finite element (FE) model for studying in vivo meniscal behavior is presented here. Further model calibration in a very controlled uniaxial low and high-rate compression loading condition is presented by comparing the model behavior against the measured high-accuracy menisci DRSA kinematics and direct tibio-femoral pressure measurement from a K-scan sensor. It is apparent that certain model aspects such as removing of the pressure sensor from the model can result in relatively large errors (14%) in contact parameters that are not reflected in the change of the measured meniscal kinematics. Changing mesh size to 1 mm by 1 mm elements increased the magnitude of all but one of the contact variables by up to 45%. This local validation using accurate localized patient-specific geometry and meniscal kinematics was needed to enhance model fidelity at the level of contact between menisci and cartilage.

Original languageEnglish (US)
Pages (from-to)2633-2638
Number of pages6
JournalJournal of Biomechanics
Issue number12
StatePublished - Aug 28 2008



  • Dynamic radiography
  • Finite elements
  • Knee

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this