Pathophysiology and Treatment of Canavan Disease

David E Pleasure, Fuzheng Guo, Olga Chechneva, Peter Bannerman, Jennifer McDonough, Travis Burns, Yan Wang, Vanessa Hull

Research output: Contribution to journalArticle

Original languageEnglish (US)
JournalNeurochemical Research
DOIs
StateAccepted/In press - Jan 1 2018

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Canavan Disease
Gene therapy
Genetic Therapy
N-acetylaspartate

Keywords

  • Aspartoacylase (encoded by ASPA)
  • Canavan disease
  • Gene therapy
  • N-acetyl-l-aspartate (NAA)
  • N-acetyltransferase 8-like (encoded by Nat8l)
  • NaDC3 (encoded by Slc13a3)
  • Vacuolar (“spongiform”) leukodystrophy

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

Cite this

Pleasure, D. E., Guo, F., Chechneva, O., Bannerman, P., McDonough, J., Burns, T., ... Hull, V. (Accepted/In press). Pathophysiology and Treatment of Canavan Disease. Neurochemical Research. https://doi.org/10.1007/s11064-018-2693-6

Pathophysiology and Treatment of Canavan Disease. / Pleasure, David E; Guo, Fuzheng; Chechneva, Olga; Bannerman, Peter; McDonough, Jennifer; Burns, Travis; Wang, Yan; Hull, Vanessa.

In: Neurochemical Research, 01.01.2018.

Research output: Contribution to journalArticle

Pleasure, David E ; Guo, Fuzheng ; Chechneva, Olga ; Bannerman, Peter ; McDonough, Jennifer ; Burns, Travis ; Wang, Yan ; Hull, Vanessa. / Pathophysiology and Treatment of Canavan Disease. In: Neurochemical Research. 2018.
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