Abstract
Coccidioidomycosis is a fungal disease caused by either Coccidioides immitis or Coccidioides posadasii. Anecdotal evidence suggests that camelids are particularly susceptible to this disease and that a relatively large percentage of pneumonias in these animals are caused by Coccidioides spp. In a search of 21 y (1992–2013) of records from the California Animal Health and Food Safety Laboratory, we found 79 cases of coccidioidomycosis diagnosed in camelids; 66 (84%) had pneumonia and 13 (16%) had lesions only in organs other than the lungs. The organs most frequently affected were lung (84%) and liver (78%). Coccidioides spp. were the cause of pneumonia in 66 of 362 (18%) camelid cases during the study period. The lesions in affected organs were multifocal-to-coalescing pyogranulomas, which in most cases were visible grossly. Ten of the 12 formalin-fixed, paraffin-embedded lung samples tested by a universal Coccidioides spp. PCR assay were positive (4 C. immitis, 2 C. posadasii); the species could not be determined in 4 of the 10 cases positive by PCR. Coccidioidomycosis is an important cause of pneumonia in camelids in California, and can be caused by either C. immitis or C. posadasii.
| Original language | English (US) |
|---|---|
| Journal | Journal of Veterinary Diagnostic Investigation |
| DOIs | |
| State | Accepted/In press - May 1 2018 |
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Keywords
- Coccidioides immitis
- Coccidioides posadasii
- Camelids
- Coccidioidesspp
- coccidioidomycosis
- pneumonia
ASJC Scopus subject areas
- veterinary(all)
Cite this
Pathology of coccidioidomycosis in llamas and alpacas. / Fernandez, Julian A.; Hidalgo, Mireia N.; Hodzic, Emir; Diab, Santiago S; Uzal, Francisco A.
In: Journal of Veterinary Diagnostic Investigation, 01.05.2018.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pathology of coccidioidomycosis in llamas and alpacas
AU - Fernandez, Julian A.
AU - Hidalgo, Mireia N.
AU - Hodzic, Emir
AU - Diab, Santiago S
AU - Uzal, Francisco A
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Coccidioidomycosis is a fungal disease caused by either Coccidioides immitis or Coccidioides posadasii. Anecdotal evidence suggests that camelids are particularly susceptible to this disease and that a relatively large percentage of pneumonias in these animals are caused by Coccidioides spp. In a search of 21 y (1992–2013) of records from the California Animal Health and Food Safety Laboratory, we found 79 cases of coccidioidomycosis diagnosed in camelids; 66 (84%) had pneumonia and 13 (16%) had lesions only in organs other than the lungs. The organs most frequently affected were lung (84%) and liver (78%). Coccidioides spp. were the cause of pneumonia in 66 of 362 (18%) camelid cases during the study period. The lesions in affected organs were multifocal-to-coalescing pyogranulomas, which in most cases were visible grossly. Ten of the 12 formalin-fixed, paraffin-embedded lung samples tested by a universal Coccidioides spp. PCR assay were positive (4 C. immitis, 2 C. posadasii); the species could not be determined in 4 of the 10 cases positive by PCR. Coccidioidomycosis is an important cause of pneumonia in camelids in California, and can be caused by either C. immitis or C. posadasii.
AB - Coccidioidomycosis is a fungal disease caused by either Coccidioides immitis or Coccidioides posadasii. Anecdotal evidence suggests that camelids are particularly susceptible to this disease and that a relatively large percentage of pneumonias in these animals are caused by Coccidioides spp. In a search of 21 y (1992–2013) of records from the California Animal Health and Food Safety Laboratory, we found 79 cases of coccidioidomycosis diagnosed in camelids; 66 (84%) had pneumonia and 13 (16%) had lesions only in organs other than the lungs. The organs most frequently affected were lung (84%) and liver (78%). Coccidioides spp. were the cause of pneumonia in 66 of 362 (18%) camelid cases during the study period. The lesions in affected organs were multifocal-to-coalescing pyogranulomas, which in most cases were visible grossly. Ten of the 12 formalin-fixed, paraffin-embedded lung samples tested by a universal Coccidioides spp. PCR assay were positive (4 C. immitis, 2 C. posadasii); the species could not be determined in 4 of the 10 cases positive by PCR. Coccidioidomycosis is an important cause of pneumonia in camelids in California, and can be caused by either C. immitis or C. posadasii.
KW - Coccidioides immitis
KW - Coccidioides posadasii
KW - Camelids
KW - Coccidioidesspp
KW - coccidioidomycosis
KW - pneumonia
UR - http://www.scopus.com/inward/record.url?scp=85047405399&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85047405399&partnerID=8YFLogxK
U2 - 10.1177/1040638718777282
DO - 10.1177/1040638718777282
M3 - Article
C2 - 29790449
AN - SCOPUS:85047405399
JO - Journal of Veterinary Diagnostic Investigation
JF - Journal of Veterinary Diagnostic Investigation
SN - 1040-6387
ER -